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Symptoms Of Yeast Infection Could Be These Bad
By Muna wa Wanjiru
Symptoms of yeast infection are some of the most annoying and if you have never suffered from the infection, you should dread the experience. This does not mean that you have to live in fear because when you have the information on symptoms of yeast infection, you will know exactly what to do. The most common yeast infection in women occurs in and around the vagina. Itching is one of the major symptom of yeast infection anywhere in the body. A part from feeling itchy, you will also experience a burning sensation and there will be pain while urinating. Cottage cheese is usually very white and you will have a discharge that looks like it. Probably the most frustrating symptom of yeast infection is the discomfort while having sexual intercourse. There will be pain and sometimes a bloody discharge.

If you have all these symptoms of yeast infection, it does not mean that you are sure that you have the yeast infection. The problem could be worse. A sexually transmitted disease is probably worse than the yeast infection. This is because it might be viral or bacterial. Therefore, to be absolutely sure of the condition, you have to see a doctor. The only time you do not have to see a doctor is when the condition has occurred to you before and you will therefore medicate again. For people who come with special cases, they should never self medicate. This people can be pregnant women, patients, children under 12 years and others. This is because their treatment plan will differ and it will make sure that their conditions are not affected negatively.

Some of the conditions that manifest themselves like symptoms of yeast infection are contact dermatitis, allergic reactions, sexually

Body's Response to Foods' Smell, Taste Could Be Diabetes Risk Factor (HealthDay)
HealthDay - THURSDAY, March 11 (HealthDay News) -- A mutation that affects how the body responds when a person smells or tastes food may play a role in the development of type 2 diabetes in some people, U.S. researchers report.
Big first trimester weight gain ups diabetes risk (Reuters)
Reuters - Women who gain weight too quickly during the first three months of pregnancy are more prone to develop pregnancy-related diabetes, new research shows.
Increasing Soda Consumption Fuels Rise in Diabetes, Heart Disease (HealthDay)
HealthDay - FRIDAY, March 5 (HealthDay News) --Increasing consumption of sugary soft drinks contributed to 130,000 new cases of diabetes, 14,000 new cases of heart disease and 50,000 more life-years burdened with heart disease in the last decade, a new U.S. study finds.
Processed Meat May Harm the Heart (HealthDay)
HealthDay - FRIDAY, March 5 (HealthDay News) -- Conventional wisdom has dictated that fat from red meat is a risk factor for heart disease, but a new analysis from Harvard researchers finds it's eating processed meat -- not unprocessed red meat -- that increases the risk for heart disease and even diabetes.
Bugs in the gut can cause obesity: study (AFP)
AFP - The bugs that help digest food may also cause the body to pack on the pounds if they are not properly regulated, a new study has found.
Bugs in the gut can cause obesity: study (AFP)
AFP - The bugs that help digest food may also cause the body to pack on the pounds if they are not properly regulated, a new study has found.
Lunchtime coffee break best for fighting diabetes (Reuters)
Reuters - Drinking coffee cuts diabetes risk, new research confirms, but you may need to enjoy your java with lunch if you want to get any benefit.
Whole Grains Take a Bite Out of Type 2 Diabetes Risk (HealthDay)
HealthDay - WEDNESDAY, March 3 (HealthDay News) -- Brown rice is better than white rice at reducing the risk of type 2 diabetes, but whole grains are the most effective at lowering the risk, study findings show.
A1c diabetes test is a better indicator of risk (Reuters)
Reuters - A test that shows blood sugar levels over a span of several weeks is not only the best way to diagnose diabetes but also may be better at identifying who is at risk of getting diabetes than standard blood sugar tests, researchers said on Wednesday.
Newer Blood Test Predicts Diabetes, Heart Disease (HealthDay)
HealthDay - WEDNESDAY, March 3 (HealthDay News) -- The newer hemoglobin A1C test predicts diabetes as well as the traditional fasting blood sugar test, but it beats that old standard in predicting a patient's future risk of heart disease and stroke, new research shows.


transmitted diseases like genital warts and herpes, pin worms and very many other conditions. For men, they will experience the same itching sensation on the foreskin of the penis. They can also be sore and tender with some whitish growth at the tip of the penis. For a throat yeast infection, you will experience extreme discomfort characterized by soreness. Other symptoms for yeast infection on skin will be flakiness coupled with itchiness. The skin can become darker with patches. For white and light people, the patches are very red.

If you have a very severe infection, you might feel tired and weak. You may experience a bloated stomach, indigestion, constipation and many others. This happens if the yeast have multiplied in your gut making the digestion of your food very compromised. There will be bacteria and other toxins that will poison your system produced by the great amount of yeast in your organs. The worse kind of the infection is where your bloodstream is infected. This means that your brain will also be affected and you might experience episodes of brain fog. Before the infection gets to this stage, you need to have taken the necessary precautions to ensure that your immunity is not totally compromised. Yeast infection is only made worse if you have an underlaying condition like cancer or AIDS. However you can engage in the good habit of building your immunity by eating healthy foods like fruits and vegetables.

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Peter Gitundu is a web administrator and has been researching and reporting on Yeast Infection for years. For more information on Symptoms Of Yeast Infection, visit his site at SYMPTOMS OF YEAST INFECTION  You Can Also Post Pour Views About Symptoms Of Yeast Infection On My Blog Here   Symptoms Of Yeast Infection

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Editorial Board
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(NaturalNews) For years, advocates of natural health have been hammering away at the message that soda causes diabetes and obesity. The soda industry, meanwhile, has remained in denial mode, mirroring the ridiculous position of the tobacco industry that "nicotine is not addictive." Soda doesn't cause diabetes, the industry claims, and it's perfectly safe to consume in essentially unlimited quantities.The Corn Refiners Association has joined the denial with its own spin campaign that seeks to convince people High-Fructose Corn Syrup (HFCS) is totally natural and completely harmless. HFCS is, of course, the primary sweetener used in sodas and soft drinks.Now comes new research presented at the American Heart Association's Cardiovascular Disease Epidemiology and Prevention annual conference i...
Nitric oxide-releasing wrap for donor organs and cloth for therapeutic socks
(American Chemical Society) Scientists in Texas are reporting development of a first-of-its-kind cloth that releases nitric oxide gas -- an advance toward making therapeutic socks for people with diabetes and a wrap to help preserve organs harvested for transplantation. The study is in ACS' Chemistry of Materials, a bi-weekly journal. (Source: EurekAlert! - Medicine and Health)
Sodium-Glucose Co-Transport Inhibitors: Progress and Therapeutic Potential in Type 2 Diabetes Mellitus
(Source: Drugs)
Diabetes drug effective if taken early
PORTLAND, Ore., March 9 (UPI) -- The sooner people with diabetes take the generic drug Metformin that helps prevent high blood sugar levels, the longer it is effective, U.S. researchers said. (Source: Health News - UPI.com)
Scotland backs saxagliptin for type-2 diabetes
People in Scotland with type-2 diabetes now have access to a wider choice of treatments after saxagliptin (Onglyza) was accepted for use within NHS Scotland. (Source: HealthcareRepublic Press Releases)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Resting Heart Rate and Metabolic Syndrome in Patients With Diabetes and Coronary Artery Disease in Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial
Prev Cardiol. ****;**:**[ndash]**. The relation between the metabolic syndrome (MetS) and resting heart rate (rHR) in patients with diabetes and coronary artery disease is unknown. The authors examined the cross-sectional association at baseline between components of the MetS and rHR and between rHR and left ventricular ejection fraction in the population from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized clinical trial. The mean rHR in the MetS group was significantly higher than in those without (68.4±12.3 vs 65.6±11.8 beats per min, P=.0017). The rHR was higher (P (Source: Preventive Cardiology)
Drug utilization of oral hypoglycemic agents in a university teaching hospital in India
Conclusion: This study strongly highlights the need for patient education or counselling on use of antidiabetic and concomitant drugs, monitoring of blood glucose and glycosylated haemoglobin (HbA1c) levels, diet control, and correction of diabetic complications. Metabolic control was poor and HbA1c monitoring was underutilized. Clinical monitoring of patients' adherence to prescribed treatments is recommended and measures should be taken to improve it. (Source: Journal of Clinical Pharmacy and Therapeutics)
JinQi-Jiangtang tablet, a Chinese patent medicine, for pre-diabetes: a randomized controlled trial
DiscussionThe aim of this study is to evaluate the effectiveness and safety of JinQi JiangTang (JQJT) tablets for the treatment of patients with pre-diabetes.Trial registrationChinese clinical trials register ChiCTR-TRC-00000401 (Source: Trials)
Non-Langerhans cell histiocytosis with isolated CNS involvement: An unusual variant of Erdheim-Chester disease
We report a 58-year-old Caucasian woman who presented with diabetes insipidus and was found to harbor a large suprasellar mass. Histopathological analysis was consistent with non-LCH. The differential diagnoses included juvenile xanthogranuloma, adult-onset xanthogranuloma, xanthoma disseminatum, Rosai-Dorfman disease, and Erdheim-Chester disease. Immunohistochemical examination demonstrated a proliferation of large lipid-laden histiocytic cells which were positive for CD68, negative for S100 protein, and showed only faint, background staining for CD1a. We present a case of an autopsy-confirmed non-Langerhans cell histiocytosis limited to the central nervous system and evaluated with both immunohistochemical and ultrastructural studies. Based on the multifocality, anatomic distribution, an...
A high-protein low-fat diet is more effective in improving blood pressure and triglycerides in calorie-restricted obese individuals with newly diagnosed type 2 diabetes
Authors: E Papakonstantinou, D Triantafillidou, D B Panagiotakos, A Koutsovasilis, M Saliaris, A Manolis, A Melidonis & A Zampelas (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus
Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) announced the commencement of the "Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus" trial (SAVOR-TIMI 53), a multicenter, randomized, double-blind, placebo-controlled Phase 4 study, to evaluate treatment with ONGLYZA? (saxagliptin), a dipeptidyl peptidase-4 (DPP4) inhibitor, in adult type 2 diabetes patients with cardiovascular risk factors. (Source: World Pharma News)
iViva Bien!: Overcoming Recruitment Challenges in a Multiple-Risk-Factor Diabetes Trial
Conclusions: Using appropriate recruitment procedures, a representative sample of Latinas can be obtained. (Source: American Journal of Health Behavior)
March is "Save Your Vision" Month
Did you know that diabetic retinopathy is a leading cause of blindness in the U.S. today? According to the National Diabetes Information Clearinghouse, between 12,000 to 24,000 new cases of blindness every year are attributed to diabetes. If you have diabetes, what can you do to protect your vision? Try to keep your blood sugar levels in a normal range. High blood sugar can damage delicate blood vessels in the eye. Visit an eye doctor regularly for checkups. If you notice any changes in your vision, call your eye doctor immediately. More from your diabetes guide... What to Know About Diabetic Retinopathy Photo courtesy of Medioimages/Photodisc/Getty Images March is "Save Your Vision" Month originally appeared on About.com Diabetes on Wednesday, March 10th, 2010 at 01:03:01.Permalink | ...
WBC linked to metabolic syndrome risk, severe psychiatric symptoms in schizophrenia
White blood cell count may be useful for predicting the metabolic syndrome and more severe psychiatric symptoms in non-diabetic patients with schizophrenia, say US researchers. (Source: MedWire News - Psychiatry)
Protect Your Kidneys, Control Diabetes, Op-ed
NOTE: The following is an op-ed piece by Susan MacNeil, manager, Nova Scotia Renal Program. Diabetes is the leading cause of kidney disease. More than 40 per cent of people that need dialysis also have diabetes. (Source: Government of Nova Scotia News Releases - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Beneficial Effects of L- and N-type Calcium Channel Blocker on Glucose and Lipid Metabolism and Renal Function in Patients with Hypertension and Type II Diabetes Mellitus
This study was undertaken to compare the efficacy of amlodipine (an inhibitor of L-type calcium channels) and cilnidipine (an inhibitor of both L-type and N-type calcium channels) in patients with hypertension and type II diabetes mellitus. Seventy-seven hypertensive patients were divided into two groups according to presence/absence of type II diabetes mellitus. In these two groups of patients, the effects of amlodipine and cilnidipine on glucose and lipid metabolism and renal function were compared. As for glucose and lipid metabolism, homeostasis model assessment insulin resistance (HOMA-R) level in the non-diabetic group and triglyceride in the diabetes group were significantly lower with cilnidipine than with amlodipine. As regards renal function in the diabetic group, estimated glome...
Paradoxical Decrease in High-Density Lipoprotein Cholesterol with Fenofibrate: A Quite Rare Phenomenon Indeed
Some recent clinical reports have suggested that paradoxical decreases in high-density lipoprotein cholesterol (HDL-C) levels after fenofibrate treatment may be quite common. These appear to occur mainly in patients with combined fibrate/statin therapy and possibly in those with low baseline HDL-C. Reports on HDL-C reductions after fenofibrate are possibly supported by the disappointing results in terms of HDL-C responses from the recent FIELD study. A survey on 581 patients treated for 1 year or longer was carried out in our Clinical Center. This indicated that paradoxical HDL-C reductions are a relatively uncommon phenomenon. Not more than 15.3% of the present series showed an HDL-C reduction, mostly of a modest degree. Further, reductions of HDL-C appear to occur mainly in individuals w...
Targeting the pentose phosphate pathway in syndrome X-related cardiovascular complications
Syndrome X is a combination or co-occurrence of several known cardiovascular risk factors (including central obesity, dyslipidemias, fatty liver disease, hyperinsulinemia, insulin resistance, and hypertension) that affects at least one in five people in developed countries. Syndrome X shortens life and increases morbidity by contributing to the development of both diabetes and cardiovascular disease. Type 1 or 2 diabetes affects approximately 170 million people globally, and these numbers are rapidly rising. In patients with diabetes, vascular diseases develop early and progress at an accelerated rate. It has recently become evident that glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme in the pentose-phosphate pathway and its reaction products play key roles in regulating...
Evaluation of risk of overall mortality in patients with type 2 diabetes receiving glipizide, glyburide, or glimepiride monotherapy
Source: Diabetes Care Area: News According to research published early online in Diabetes Care, glimepiride may be the preferred sulfonylurea in those with underlying coronary artery disease (CAD). &nbsp; Researchers evaluated the relationship of individual sulfonylureas and the risk of overall mortality in a cohort of patients with type 2 diabetes. The retrospective cohort study was conducted using an academic health centre enterprise-wide electronic health record (EHR) system to identify 11,141 patients with type 2 diabetes (4,279 initiators of monotherapy with glyburide, 4,325 initiators of monotherapy with glipizide, and 2,537 initiators of monotherapy with glimepiride), aged &gt;18 years, with and without a history of CAD, and not on insulin or a non-insulin injectable at baselin...
DURATION-1: Exenatide once weekly produces sustained glycaemic control and weight loss
Source: Diabetes Care Area: News According to research published early online in Diabetes Care, exenatide once weekly elicited sustained improvements in glycaemic control and body weight through 52 weeks of treatment. &nbsp; The results were obtained from a sub-analysis of the DURATION-1 trial, in which the safety and efficacy of 30 weeks of treatment with the exenatide once weekly (2mg) was compared to exenatide twice daily, in 295 patients with type 2 diabetes. &nbsp; The sub analysis evaluated the safety and efficacy of exenatide once weekly in a) patients who continued treatment for an additional 22 weeks (52 weeks total), and b) patients who switched from exenatide twice a day to exenatide once weekly after 30 weeks. A total of 258 patients entered the 22-week open-ended asse...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations
Conclusions: The study shows a relatively high proportion of GCK mutations among individuals with GCK-like phenotype, confirming the effectiveness of carefully applied clinical criteria prior to genetic testing. In the Czech MODY registry, GCK-MODY represents the biggest subgroup of MODY (35%). We report several prevalent GCK mutations with a likely founder effect in the Czech population. Furthermore, our results provide ground for a possible recommendation to reinspect all negative results previously obtained by screening using dHPLC. (Source: Pediatric Diabetes)
Relation of subepicardial adipose tissue thickness and clinical and metabolic parameters in obese prepubertal children
Conclusions: Our study on obese prepubertal children showed that SATT was significantly correlated with age, BMI, WC, HC, MAC, TSF, insulin, and HOMA-IR. (Source: Pediatric Diabetes)
Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies
Delli AJ, Lindblad B, Carlsson A, Forsander G, Ivarsson S-A, Ludvigsson J, Marcus C, Lernmark Å; for the Better Diabetes Diagnosis (BDD) Study Group. Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies. Aim: To determine whether type 1 diabetes mellitus (T1DM) patients, having parents who immigrated to Sweden, have increased T1DM risk before 18 yr compared with countries of origin. We also determined whether they have different human leukocyte antigen (HLA) genetic markers and islet autoantibodies at diagnosis compared with Swedish patients. Methods: A total of 1988 (53% males) newly diagnosed and confirmed T1DM patients (Source: Pediatric Diabetes)
Use of continuous glucose monitoring in young children with type 1 diabetes: implications for behavioral research
Conclusions: CGM is an acceptable research tool for obtaining glucose data in young children with T1DM and has been used previously in older children and adults. CGM may be particularly useful in young children who often experience more glucose variability. Data obtained via CGM are richer and more detailed than traditional SMBG data and allow for analyses to link blood glucose with behavior. (Source: Pediatric Diabetes)
Dexamethasone effective for treating diabetic macular edema
Intravitreous treatment with dexamethasone is well tolerated and significantly improves visual acuity in patients with persistent diabetic macular edema, report researchers. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Evaluation of neopterin levels in patients undergoing hemodialysis
Neopterin is a diagnostic or a prognostic biomarker for several pathologies including renal diseases. However, the association between neopterin status and causative main reasons such as diabetes and hypertension for renal disease remains unclear. The aim of the study was to evaluate neopterin levels in diabetes and hypertension patients treated with/without hemodialysis. According to primary renal disorders, the patients undergoing hemodialysis were classified into 4 groups as diabetic nephropathy, hypertensive nephropathy, reflux nephropathy or interstitial nephritis, and others. The controls consisted of healthy subjects, hypertensive subjects, and diabetic individuals without any renal disorder. In the study, both urinary and serum neopterin levels were measured using high performance ...
Analysis of Health Utility Data When Some Subjects Attain the Upper Bound of 1: Are Tobit and CLAD Models Appropriate?
Conclusions: When the intention of the analysis is to inform an economic evaluation, and the utilities should be bounded above at 1, CLAD, and Tobit methods were biased. OLS coupled with robust standard errors or the nonparametric bootstrap is recommended as a simple and valid approach. (Source: Value in Health)
Insulin Regimens in Type 2 Diabetes
To the Editor: In the Treating to Target in Type 2 Diabetes (4-T) study, Holman et al. (Oct. 29 issue)1 ... (Source: New England Journal of Medicine)
The Predictors of Patient&#x2013;Physician Race and Ethnic Concordance: A Medical Facility Fixed-Effects Approach
To examine the predictors of patient[ndash]physician race/ethnicity concordance among diabetes patients in an integrated delivery system. Kaiser Permanente's Northern California Diabetes Registry of 2005. Logistic regression predicted concordance for each racial/ethnic group. Availability of a concordant physician, whether a patient chose their physician, and patient language were main explanatory variables. The study population consisted of 109,745 patients and 1,750 physicians. Patients who chose their physicians were more likely to have a same race/ethnicity physician with OR of 2.2 (95 percent CI 1.74[ndash]2.82) for African American patients, 1.71 (95 percent CI 1.44[ndash]2.04) for Hispanic patients, 1.11 (95 percent CI 1.04[ndash]1.18) for white patients, and 1.38 (95 percent CI 1.2...
Warnings, Recommendations Fail to Improve Monitoring of Use of Atypical Antipsychotic Drugs
An important warning about atypical, or second-generation, antipsychotic drugs and a connection to increased risk for diabetes and hyperglycemia didn't make it to primary care physicians, according to a new study in the Archives of General Psychiatry. (Source: AAFP Clinical Care and Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Estimated County-Level Prevalence of Diabetes and Obesity--United States, 2007 [From the Centers for Disease Control and Prevention]
(Source: JAMA)
Link Between Hepatitis C And Insulin Resistance Surprises Scientists
Scientists in Australia found that when they studied insulin resistance in people with Hepatitis C little or none of it was in the liver and nearly all the insulin resistance occured in muscle, which surprised them because Hepatitis C is a liver disease that not only leads to cirrhosis and cancer, but also makes people three to four times more likely to develop Type 2 diabetes. You can read about the study that led to these findings in the March 2010 issue of the journal Gastroenterology, which is also available online... (Source: Health News from Medical News Today)
Link Between Hepatitis C And Insulin Resistance Surprises Scientists
Scientists in Australia found that when they studied insulin resistance in people with Hepatitis C little or none of it was in the liver and nearly all the insulin resistance occured in muscle, which surprised them because Hepatitis C is a liver disease that not only leads to cirrhosis and cancer, but also makes people three to four times more likely to develop Type 2 diabetes... (Source: Diabetes News From Medical News Today)
10 Tips to Ease Concerns About Your Weight
Given the focus on weight by the health establishment, the government and the media, it is not surprising that many people in this country are anxiously asking the same question. And there is no shortage of recommendations out there directing people to lose weight with this or that diet, lifestyle program or eating regimen. Unfortunately, the research over the last 25 years is quite clear. There is simply no evidence that any of these approaches results in long-term weight loss for the vast majority of people who engage in them. There are no exceptions and none of the approaches (low fat, low calorie, low carb, etc.) work any better than any of the others. Even more unfortunately however, this complete lack of evidence does not stop people from being seduced into trying to lose weight with...
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats [Research Articles]
In this study, we investigated the effect of FXR activation by 6-ethyl-chenodeoxycholic acid, (6E-CDCA, 10 mg/kg) on insulin resistance and liver and muscle lipid metabolism in fa/fa rats and compared its activity with rosiglitazone (10 mg/kg) alone or in combination with 6E-CDCA (5 mg/kg each). In comparison to lean (fa/+), fa/fa rats on a normal diet developed insulin resistance and liver steatosis. FXR activation protected against body weight gain and liver and muscle fat deposition and reversed insulin resistance as assessed by insulin responsive substrate-1 phosphorylation on serine 312 in liver and muscles. Activation of FXR reduced liver expression of genes involved in fatty acid synthesis, lipogenesis, and gluconeogenesis. In the muscles, FXR treatment reduced free fatty acid synth...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Glucose stimulates cholesterol 7{alpha}-hydroxylase gene transcription in human hepatocytes [Research Articles]
This study uncovers a novel link between hepatic glucose metabolism and bile acid synthesis. Glucose induction of bile acid synthesis may have an important implication in metabolic control of glucose, lipid, and energy homeostasis under normal and diabetic conditions. (Source: The Journal of Lipid Research)
Insulin Glargine QD Equivalent to Insulin Detemir BID for Type 2 Diabetics
Once-daily insulin glargine and twice-daily insulin detemir provided similar glycemic control for insulin-na?ve type 2 diabetics in a noninferiority trial. Reuters Health Information (Source: Medscape Medical News Headlines)
Acute necrotizing pancreatitis with pancreatic abscess due to
Sonavane A, Baradkar V, Salunkhe P, D&#x0027;Souza D, Kumar SIndian Journal of Medical Microbiology 2010 28(1):64-67Acute pancreatitis occasionally presents as pancreatic abscess with complications like pleural effusion and ascites. There are several pre-disposing factors, the most common being cholelithiaisis, alcohol abuse, infective causes, trauma, and metabolic causes such as diabetic ketoacidosis, while some cases are idiopathic. Here, we report a rare case of acute necrotizing pancreatitis in a 40-year-old male who presented with pain in the abdomen, ascites and left basal pleural effusion. A computerized tomography (CT) scan showed findings suggestive of pancreatic necrosis, with abscess formation and free-fluid surrounding area. The aspirated pus sample was processed for Gram stain...
The Role of Exercise-Induced Myokines in Muscle Homeostasis and the Defense against Chronic Diseases
In conclusion, exercise-induced myokines appear to be involved in mediating both systemic as well as local anti-inflammatory effects. (Source: Journal of Biomedicine and Biotechnology)
Recurrent hypoglycaemia in a type 2 diabetes patient ? diagnostic difficulties
Hypoglycaemia is the most frequent acute complication of diabetes, regardless of the type of diabetes and the treatment method. Hormonally active tumours of the pancreas, insulinomas, which belong to digestive tract neuroendocrine tumours, constitute one of the less frequent causes of hypoglycaemia. This paper presents a case of a 60-year-old type 2 diabetes patient with recurrent hypoglycaemic events, in whom an insulin-secreting hepatic neuroendocrine tumour was diagnosed. We suggest performing a diagnostic workup taking into consideration insulinoma in patients with diabetes who experience frequent otherwise inexplicable hypoglycaemic events, particularly when they recur despite decreased dose or discontinuation of hypoglycaemic agents. (Source: Articles of Archives of Medical Science -...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Adrenocorticotrophic hormone secreting pheochromocytoma
We report a rare case of pheochromocytoma of the adrenal gland presenting as Cushing syndrome. A 30 year old woman presented with pain in the left loin and classical Cushingoid features. She was a diabetic and hypertensive on treatment. Magnetic resonance imaging of the abdomen revealed a 3.5 x 3 cm mass in the left adrenal gland. Urine analysis revealed an elevated 24 hr urinary cortisol level. Clinical diagnosis was Cushing syndrome due to functioning left adrenal tumor, and hence left adrenalectomy was performed laparoscopically. Histopathological examination revealed adrenal pheochromocytoma. Immunohistochemical analysis of the tumor was positive for adrenocorticotrophic hormone and chromogranin. (Source: Indian Journal of Urology)
Assessment of plantar pressure and balance in patients with diabet
Conclusions: The data reveal a correlation between postural oscillation and peak plantar pressure on the hindfoot. (Source: Articles of Archives of Medical Science - TERMEDIA publishing house)
Bristol-Myers Squibb and AstraZeneca Announce the Commencement of the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus Trial (SAVOR-TIMI 53)
PRINCETON, N.J. & WILMINGTON, Del.--(HSMN NewsFeed)--Bristol-Myers Squibb Company (NYSE: BMY ) and AstraZeneca (NYSE: AZN ) today announced the commencement of the “Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus” tr... Biopharmaceuticals, Cardiology, EndocrinologyBristol-Myers Squibb, AstraZeneca, ONGLYZA, saxagliptin, diabetes (Source: HSMN NewsFeed)
Bezafibrate and serum amyloid A-low-density lipoprotein complex in patients with type 2 diabetes mellitus and hypertriglyceridemia.
Authors: Kotani K, Satoh N, Yamada T PMID: 20206863 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Clinical factors that influence the cardiovascular morbidity in patients with type II Diabetes Mellitus.
Authors: Kyriazis I, Mendrinos D, Saridi M PMID: 20206869 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Anemia in diabetic patients at an internal medicine ward: Clinical correlates and prognostic significance.
CONCLUSION: Frequency of anemia was increased in diabetic patients admitted to the Internal Medicine Departments, compared to the studies performed on ambulatory patient populations. Anemia was multifactorial and associated with higher mortality, predominantly from infections. Males with albuminuria and heart failure were at higher risk of death. PMID: 20206878 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Children?s launches new stem cell Web site
By Jonathan Kraft, president of The Kraft Group and New England Patriots As a long-time supporter of stem cell research, I&#8217;m proud to announce the launch of a new Children&#8217;s Hospital Boston Web site that we hope will demystify the science of stem cells and answer some of the public&#8217;s questions about them. For the past three and a half years, my wife, Patti, and I have served as co-chairs of Children&#8217;s Hospital Boston?s Stem Cell Task Force because we believe that stem cells hold incredible promise for the future of health care. During this time I?ve gotten to know Len Zon and George Daley, the two physician-scientists who head up the hospital?s Stem Cell Research Program, and I believe that the work they are doing will revolutionize health care.They?ve expl...
Bilateral carpal tunnel syndrome in a child with type 1 diabetes mellitus
Duru Nilgun Selcuk, Acar Hurtan, Ayta Semih, Elevli MuratNeurology India 2010 58(1):136-137 (Source: Neurology India)
Antidiabetic Effect of Gynostemma pentaphyllum Tea in Randomly Assigned Type 2 Diabetic Patients*
This study shows a prompt improvement of glycemia and insulin sensitivity, and thereby provides a basis for a novel, effective, and safe approach, using tea, to treat type 2 diabetic patients.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
High basic fibroblast growth factor increases CHD risk in Type 2 diabetics
Elevated plasma basic fibroblast growth factor immunoreactivity increases coronary heart disease risk in men with Type 2 diabetes, report researchers. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Licorice ? or more?
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0029-1224123AbstractA 57 yr old man presented to endocrinology clinic with a six year history of poorly controlled hypertension which was treated with Metoprolol 200&#8201;mg/day and Enalapril 20&#8201;mg/day. He was asymptomatic but incidentally hypokalaemia was detected while having cholecystectomy, two years prior to his clinic appointment. He had never been on diuretics or laxatives. He was started on potassium supplements (120&#8201;mmol/d) and advised to increase dietary potassium by the surgical team. A detailed personal history revealed ingestion of 300&#8211;500&#8201;g licorice per day. Physical examination was unremarkable apart from increased blood pressure of 180/105&#8201;mmHg. Following the initial visit, his serum electrolyes (K+3....
Lipid Peroxidation and Antioxidant System in Rats Acutely Treated with Acetone
The objective of the present study was to determine the effects of acute treatment (AT) with acetone on the oxidative and metabolic status of rats. The AT group (n=16) was treated by gavage with a single administration of 7.0&#8201;g acetone/kg body weight at a concentration of 25% (m/v). Eight rats were euthanized 6&#8201;h later (AT6) and eight 24&#8201;h later (AT24). Acetone levels were determined in blood and urine and oxidative parameters were analyzed by determining thiobarbituric acid reactive species (TBARS, indicators of lipid peroxidation) and reduced glutathione (GSH) and vitamin E as antioxidant parameters. Serum glucose, blood cholesterol and triglycerieds and hepatic fat were also determined. The results indicated a significant difference in the hepatic oxidative parameters,...
Genetic Associations of IL1RN Polymorphisms with Metabolic Syndrome in a Korean Population
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1248288AbstractMetabolic syndrome (MetS) is rapidly growing into one of the major public health issues worldwide. Interleukin 1 receptor antagonist (IL1Ra) functions as a competitor of proinflammatory cytokines and has an important role in metabolic functions, including insulin secretion. To identify the relationship between the interleukin 1 receptor antagonist gene and MetS, we genotyped nine single nucleotide polymorphisms (SNPs) in the gene using direct sequencing in 66 MetS patients and 346 normal subjects in the Korean population. Among the nine polymorphisms, after adjusting for age and sex, rs928940 (G&gt;T) showed a significant association with MetS in the codominant ( 0.023) and recessive models ( 0.011). Also, rs315952 (C&gt;T) exh...
Type 2 diabetes mellitus: A risk factor for
Conclusion: Diabetic patients are more prone and at risk to acquire H. Pylori infection. Therefore proper monitoring of blood glucose level and screening for H. pylori infection are effective preventive measures for this life threatening infection. (Source: International Journal of Diabetes in Developing Countries)
Hypoglycemic effect of aqueous extract of
Conclusion: The aqueous extract of Trichosanthes dioica has antihyperglycemic action. (Source: International Journal of Diabetes in Developing Countries)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Free radical scavenging activity of
Rathod N R, Raghuveer I, Chitme H R, Chandra RIndian Journal of Pharmaceutical Sciences 2009 71(6):615-621Swarnabhasma , an Ayurvedic preparation containing Calotropis gigantea R. Br. (Asclepiadaceae) is extensively used by Ayurvedic physicians for treatment of diabetes mellitus, bronchial asthma, rheumatoid arthritis and nervous disorders. In the present study, we report the effect of chloroform extracts of Calotropis gigantea leaf and flower on free radical scavenging activity, and lipid profile in streptozotozin-induced diabetic rats. The lipid peroxidation, superoxide dismutase, and catalase were measured in liver homogenate and serum glutamic pyruvic transaminase, serum glutamic oxaloacetic transaminase, alkaline phosphatase, lipid profile were measured in blood serum. Administration ...
High basic fibroblast growth factor increases CHD risk in Type 2 diabetics
Elevated plasma basic fibroblast growth factor immunoreactivity increases coronary heart disease risk in men with Type 2 diabetes, report researchers. (Source: MedWire News - Heart Failure)
Blunting of the Heart Rate Response to Adenosine and Regadenoson in Relation to Hyperglycemia and the Metabolic Syndrome
Adenosine and regadenoson cause an increase in heart rate (HR) during myocardial perfusion imaging (MPI). It has been shown that patients with diabetes mellitus have a blunted HR response due to cardiac autonomic dysfunction. It is not known whether the HR response is related to hyperglycemia and the metabolic syndrome (MS). HR changes were assessed in 2,000 patients (643 with diabetes mellitus [DM]) in the Adenoscan Versus Regadenoson Comparative Evaluation for Myocardial Perfusion Imaging (ADVANCE MPI 1 and ADVANCE MPI 2) trials in relation to MS status and blood sugar level on the day of MPI. The HR response was lower in patients with MS (32.43 ± 0.52% vs 36.15 ± 0.71%, p (Source: The American Journal of Cardiology)
Prognostic Value of an Exaggerated Exercise Blood Pressure Response in Patients With Diabetes Mellitus and Known or Suspected Coronary Artery Disease
The prognostic value of an exaggerated exercise systolic blood pressure response (EESBPR) remains controversial. Our aim was to assess whether an EESBPR is associated with the long-term outcome in patients with diabetes mellitus and known or suspected coronary artery disease (CAD). From an initial population of 22,262 patients with known or suspected CAD who underwent treadmill exercise electrocardiography or exercise echocardiography at our institution, 2,591 patients with a history of diabetes mellitus were selected for the present study. EESBPR was defined as systolic blood pressure >220 mm Hg during exercise. The end points were all-cause mortality and hard events (ie, death or myocardial infarction). A total of 236 patients (9.1%) developed an EESBPR during the tests. During a mean fo...
Does Getting Fat Protect against Fat?
Everyone knows that obesity is bad for your health. Packing on the pounds, we&rsquo;re told, leads to all sorts of medical problems: high cholesterol, insulin resistance, greater risk of diabetes and heart disease. But researchers at the University of Texas Southwestern Medical Center see things a little differently. In a paper in the journal Trends in Endocrinology and Metabolism [see http://bit.ly/bKaP33 ], they argue that being fat can actually protect us from these disorders. [More] (Source: Scientific American - Official RSS Feed)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Macular ischaemia after intravitreal bevacizumab injection in patients with central retinal vein occlusion and a history of diabetes and vascular disease
(Source: British Journal of Ophthalmology)
Vision-related quality of life in persons with unilateral branch retinal vein occlusion using the 25-item National Eye Institute Visual Function Questionnaire
Conclusions BRVO is a retinal vascular disease that is associated with a decrease in vision-related quality of life as determined by the VFQ-25. A decrease in VFQ-25 score is correlated with involved eye visual acuity, even when good visual acuity is maintained in the uninvolved eye. (Source: British Journal of Ophthalmology)
Taxing junk food improves health outcomes, study finds
(Source: BMJ Online First)
Obesity As Protection Against Metabolic Syndrome, Not Its Cause
The collection of symptoms that is the metabolic syndrome - insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke - are all related to obesity, but, according to a review in the March 9th issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are... (Source: Cholesterol News From Medical News Today)
Obesity As Protection Against Metabolic Syndrome, Not Its Cause
The collection of symptoms that is the metabolic syndrome - insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke - are all related to obesity, but, according to a review in the March 9th issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are. In fact, says Roger Unger of the University of Texas Southwestern at Dallas, obesity is the body's way of storing lipids where they belong, in fat tissue, in an effort to protect our other organs from lipids' toxic effects... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Obesity as protection against metabolic syndrome, not its cause
The collection of symptoms that is the metabolic syndrome -- insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke -- are all related to obesity, but, according to a new review not in the way you probably think they are. (Source: ScienceDaily Headlines)
Intermountain Healthcare And Toshiba Announce Ultrasound Substudy Of FaCTor64 - Speckle Tracking By Echo
Cardiovascular death is the most common cause of mortality among Type 2 diabetics and claims the lives of millions each year, with many diabetics experiencing their first "symptom" as a heart attack or sudden death. Understanding that diabetics are at high risk for Coronary Heart Disease (CHD) and that many with the disease are asymptomatic, Toshiba America Medical Systems, Inc., has sponsored Speckle Tracking by Echo, a faCTor64 substudy using Toshiba's Wall Motion Tracking ultrasound technology... (Source: Health News from Medical News Today)
Higher Fast Food Prices Lead To Lower Weight, Diabetes Risk
A new study that followed participants for 20 years shows both weight and risk for diabetes decreased for people in communities where fast food prices increased. The University of North Carolina at Chapel Hill study, published in the March 8, 2010, issue of Archives of Internal Medicine, also showed the reverse when fast food prices fell, then consumption, weight and diabetes risks rose... (Source: Health News from Medical News Today)
Intermountain Healthcare And Toshiba Announce Ultrasound Substudy Of FaCTor64 - Speckle Tracking By Echo
Cardiovascular death is the most common cause of mortality among Type 2 diabetics and claims the lives of millions each year, with many diabetics experiencing their first "symptom" as a heart attack or sudden death. Understanding that diabetics are at high risk for Coronary Heart Disease (CHD) and that many with the disease are asymptomatic, Toshiba America Medical Systems, Inc... (Source: Cardiovascular / Cardiology News From Medical News Today)
Higher Fast Food Prices Lead To Lower Weight, Diabetes Risk
A new study that followed participants for 20 years shows both weight and risk for diabetes decreased for people in communities where fast food prices increased. The University of North Carolina at Chapel Hill study, published in the March 8, 2010, issue of Archives of Internal Medicine, also showed the reverse when fast food prices fell, then consumption, weight and diabetes risks rose... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Eye Disease Linked To Weakened Brain Power In People With Diabetes
Diabetic retinopathy, the leading cause of blindness in the UK's working-age population, could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research¹ announced this week at leading health charity Diabetes UK's Annual Professional Conference. The study looked at 1,066 people with Type 2 diabetes aged between 60 and 75 years old. Participants completed seven tests looking at memory, logic and concentration to establish their level of brain function... (Source: Health News from Medical News Today)
Is There A Link Between Drinking Too Many Sugary Drinks And Diabetes?
A new study claims that having sugary drinks every day could put people at a greater risk of developing Type 2 diabetes and heart disease. American researchers found that the excessive consumption of sugary drinks, which can contain up to 200 calories each, contributed to 130,000 cases of Type 2 diabetes and 14,000 cases of heart disease between 1990 and 2000 in the USA. The researchers also concluded that sugary drinks are fuelling the obesity epidemic... (Source: Health News from Medical News Today)
Eye Disease Linked To Weakened Brain Power In People With Diabetes
Diabetic retinopathy, the leading cause of blindness in the UK's working-age population, could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research¹ announced this week at leading health charity Diabetes UK's Annual Professional Conference. The study looked at 1,066 people with Type 2 diabetes aged between 60 and 75 years old... (Source: Diabetes News From Medical News Today)
Is There A Link Between Drinking Too Many Sugary Drinks And Diabetes?
A new study claims that having sugary drinks every day could put people at a greater risk of developing Type 2 diabetes and heart disease. American researchers found that the excessive consumption of sugary drinks, which can contain up to 200 calories each, contributed to 130,000 cases of Type 2 diabetes and 14,000 cases of heart disease between 1990 and 2000 in the USA... (Source: Diabetes News From Medical News Today)
Surprising findings about Hepatitis C and insulin resistance
(Research Australia) We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance was in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Starting treatment early doubles chance of success for people with diabetes
(GolinHarris International) The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association. (Source: EurekAlert! - Medicine and Health)
Surprising findings about Hepatitis C and insulin resistance
Scientists have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance was in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease. (Source: ScienceDaily Headlines)
Starting treatment early doubles chance of success for people with diabetes
The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a new study. (Source: ScienceDaily Headlines)
Soft Drink and Juice Consumption and Risk of Physician-diagnosed Incident Type 2 Diabetes: The Singapore Chinese Health Study
Soft drinks and other sweetened beverages may contribute to risk of type 2 diabetes and obesity. However, research has not addressed higher risk and Asian populations. The authors examined the association between soft drinks and juice and the risk of type 2 diabetes among Chinese Singaporeans enrolled in a prospective cohort study of 43,580 participants aged 45&ndash;74 years and free of diabetes and other chronic diseases at baseline. The incidence of physician-diagnosed type 2 diabetes was assessed by interview and validated; 2,273 participants developed diabetes during follow-up. After adjustment for potential lifestyle and dietary confounders, participants consuming &ge;2 soft drinks per week had a relative risk of type 2 diabetes of 1.42 (95% confidence interval (CI): 1.25, 1.62) comp...
The Association Between the Peroxisome Proliferator-Activated Receptor-{gamma}2 (PPARG2) Pro12Ala Gene Variant and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis
The peroxisome proliferator-activated receptor- gene (PPARG) has been implicated in the etiology of type 2 diabetes mellitus and has been investigated in numerous epidemiologic studies. In this Human Genome Epidemiology review, the authors assessed this relation in an updated meta-analysis of 60 association studies. Electronic literature searches were conducted on September 14, 2009. Population-based cohort, case-control, cross-sectional, or genome-wide association studies reporting associations between the PPARG Pro12Ala gene variant (rs1801282) and type 2 diabetes were included. An updated literature-based meta-analysis involving 32,849 type 2 diabetes cases and 47,456 controls in relation to the PPARG Pro12Ala variant was conducted. The combined overall odds ratio, calculated by per-all...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Alendronate Induces Mineralization in Mouse Osteoblastic MC3T3-E1 Cells: Regulation of Mineralization-Related Genes
In conclusion, low-dose alendronate induced mineralization in mouse osteoblastic cells. The regulation of PC-1, osteocalcin and ALP by alendronate might play some role in these effects.[...]© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Diabetes classification switch to force wave of patient reviews
GPs will have to re-assess around 40% of people with type-1 diabetes and 6% with type-2 diabetes, following the development of a new classification system. (Source: HealthcareRepublic Independent Nurse News)
Diabetes, Insulin and Alzheimer's Disease
series:Research and Perspectives in Alzheimer's DiseaseNeurons share more similarities with insulin-producing pancreatic islet cells than with any other cell type. The root of this similarity may lie in the islet?s evolution from an ancestral insulin-producing neuron. The islet-neuron connection becomes less surprising as we learn more about insulin?s involvement in functions far from its traditional role in mediating glucose uptake in muscle. The ... (Source: Springer Biomedical Sciences titles)
Simple pharmacometric tools for oral anti-diabetic drug development: competitive landscape for oral non-insulin therapies in type 2 diabetes
In conclusion, the ability of system-specific parameters to predict HbA1c provides a tool to predict the expected efficacy profile from abbreviated dose-finding trials. To be commercially viable, new drugs should improve [Delta]HbA1c by about 0.8% or more and possess safety profiles similar to newer anti-diabetic agents. Thus, this study proposes a suite of simple yet powerful tools to guide type-2-diabetes drug development. Copyright © 2010 John Wiley & Sons, Ltd. (Source: Biopharmaceutics and Drug Disposition)
Another Advantage to Nursing the Baby
Newborn mice who receive their mother's milk experience a biological process that boosts their metabolism, possibly lowering the risk of obesity and diabetes in adulthood, according to a new study. Breast-feeding confers several protective benefits in... (Source: OrlandoSentinel: Medical Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Rho kinase and protein kinase C involvement in vascular smooth muscle myofilament calcium sensitization in arteries from diabetic rats
Conclusions and implications: We conclude that in DM enhanced myofilament Ca2+ sensitivity is mainly manifested in muscular-type blood vessels and thus likely to contribute to the development of hypertension. Both PKC and, in particular, ROCK are involved in this phenomenon. This highlights their potential usefulness as drug targets in the pharmacological management of DM-associated vascular dysfunction. (Source: British Journal of Pharmacology)
Diabetics with a more interactive relationship style have reduced mortality
Patients with diabetes who have a ?more interactive? relationship style and who are more inclined to seek social support when needed have lower 5-year mortality than those who do not, show study results. (Source: MedWire News - Diabetes)
Crevicular fluid matrix metalloproteinase-8, -13, and TIMP-1 levels in type 2 diabetics
Conclusions: Within the limits of this study, DM does not seem to significantly affect GCF levels of MMP-8, MMP-13, TIMP-1 or clinical periodontal status. (Source: Oral Diseases)
Laparoscopic radical prostatectomy is feasible and effective in 'fit' senior men with localized prostate cancer
OBJECTIVETo assess the effect of age and comorbidity on short-term complications, long-term continence and oncological outcome after laparoscopic radical prostatectomy (LRP) for localized prostate cancer.PATIENTS AND METHODS In all, 2048 consecutive men underwent LRP for localized prostate cancer in one institution. Comorbidity was assessed using the Charlson index. Short-term postoperative complications, transfusion rate, duration of hospital stay, long-term continence and oncological outcome were analysed by age and comorbidity classes.RESULTS Of the 2048 men, 297 were aged [ge]70 years and 281 had a Charlson index of >0 (mainly diabetes 31%, chronic pulmonary disease 26%, prior other nonmetastatic cancer 16%, prior myocardial infarction 12%). Compared with younger men, senior men had si...
Comparison of sex hormonal and metabolic profiles between omnivores and vegetarians in pre- and post-menopausal women.
Authors: Karelis AD, Fex A, Filion ME, Adlercreutz H, Aubertin-Leheudre M The purpose of the present study was to investigate the sex hormonal and metabolic profiles in vegetarians and compare these with the profiles in omnivores. The design of the present study was cross-sectional. The study sample of pre- and post-menopausal women included forty-one omnivores and twenty-one vegetarians. Thereafter we determined: (1) plasma sex hormones, (2) fasting insulin, NEFA as well as apo-A and apo-B, (3) BMI, (4) a dietary profile (3 d dietary records), (5) physical activity and (6) total faecal excretion per 72 h and total urinary excretion per 72 h. Vegetarians showed higher levels of sex hormone-binding globulin (SHBG), apo-A, total faecal excretion per 72 h and total fibre intake as well as...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Effects of metformin on glucose metabolism of perfused rat livers.
Authors: de Souza Silva FM, Rocha Alves da Silva MH, Bracht A, Eller GJ, Constantin RP, Yamamoto NS Although metformin has been used to treat type 2 diabetes for several decades, the mechanism of its action on glucose metabolism remains controversial. To further assess the effect of metformin on glucose metabolism this work was undertaken to investigate the acute actions of metformin on glycogenolysis, glycolysis, gluconeogenesis, and ureogenesis in perfused rat livers. Metformin (5 mM) inhibited oxygen consumption and increased glycolysis and glycogenolysis in livers from fed rats. In perfused livers of fasted rats, the drug (concentrations higher than 1.0 mM) inhibited oxygen consumption and glucose production from lactate and pyruvate. Gluconeogenesis and ureogenesis from alanine we...
Effect of Long-Term Intraperitoneal Zinc Administration on Liver Glycogen Levels in Diabetic Rats Subjected to Acute Forced Swimming.
This study aims to examine the effect of zinc administration on liver glycogen levels of rats in which diabetes was induced with streptozotocin and which were subjected to acute swimming exercise. The study was conducted on 80 adult Sprague-Dawley male rats, which were equally allocated to eight groups: group 1, general control; group 2, zinc-administrated control; group 3, zinc-administrated diabetic control; group 4, swimming control; group 5, zinc-administrated swimming; group 6, zinc-administrated diabetic swimming; group 7, diabetic swimming; group 8, diabetic control group. In order to induce diabetes, animals were injected with 40 mg/kg intraperitoneal (ip) streptozotocin. The injections were repeated in the same dose after 24 h. Animals which had blood glucose at or above 300 mg/dl...
Evidence of Interaction between Type 2 Diabetes Susceptibility Genes and Dietary Fat Intake for Adiposity and Glucose Homeostasis-Related Phenotypes
J Nutrigenet Nutrigenomics 2009;2:225–234 (DOI:10.1159/000259341) (Source: Karger Publishers)
Add diabetes to Ont. school policy: parents
Some Ontario families with school-aged children requiring medical attention for conditions such as Type 1 diabetes have major concerns about a health and education policy currently under review. (Source: CBC | Health)
Randomized Controlled Trial of an Intravitreous Dexamethasone Drug Delivery System in Patients With Diabetic Macular Edema [Clinical Trial]
Conclusions&nbsp; In eyes with persistent DME, treatment with 700 &micro;g of intravitreal dexamethasone DDS is well tolerated and produces significant improvements in BCVA, central retinal thickness, and fluorescein leakage compared with observation (statistically significant at day 90). Application to Clinical Practice&nbsp; Dexamethasone DDS, 700 &micro;g, may have potential as a treatment for persistent DME. Trial Registration&nbsp; clinicaltrials.gov Identifier: NCT00035906 (Source: Archives of Opthalmology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Errors in Byline and Text in: Association Between Erythropoietin Gene Polymorphisms and Diabetic Retinopathy [Correction]
(Source: Archives of Opthalmology)
Lack of Association Between Thiazolidinediones and Macular Edema in Type 2 Diabetes: The ACCORD Eye Substudy [Clinical Sciences]
Conclusions&nbsp; In a cross-sectional analysis of data from the largest study to date, no association was observed between thiazolidinedione exposure and DME in patients with type 2 diabetes; however, we cannot exclude a modest protective or harmful association. Trial Registration&nbsp; clinicaltrials.gov Identifier: NCT00542178 (Source: Archives of Opthalmology)
Food Surcharges and Subsidies: Putting Your Money Where Your Mouth Is [Editorial]
(Source: Archives of Internal Medicine)
Alcohol Consumption, Weight Gain, and Risk of Becoming Overweight in Middle-aged and Older Women [Original Investigation]
Conclusion&nbsp; Compared with nondrinkers, initially normal-weight women who consumed a light to moderate amount of alcohol gained less weight and had a lower risk of becoming overweight and/or obese during 12.9 years of follow-up. (Source: Archives of Internal Medicine)