Learn How To Set Realistic Goals For Your Weight Loss By Acomplia Rimonabant By David Albert Weight loss is not something as a blind's man journey or it's not something to take a dosage at night and walk up in the morning to lose weight. Weight loss is a long way process to lose weight and keeping the weight off with healthy lifestyle. To start your weight loss journey, the best way is to keep your weight loss goal worksheet at hand so you can realistically set your plans. This weight loss goal worksheet helps you keep track of your weight loss journey so you can monitor that how much your weight loss plan got successful. This weight loss goal worksheet has some exercise, a little bet dieting and Acomplia as a weight loss drug. If you want to get your body back to shape but have found that most of the diet plans have not worked for you. Then take a look at popular weight loss drug Acomplia. Acomplia weight loss drug is a diet pill also cures obesity which will reduce extra fat and get you into shape. Acomplia weight loss drug does not only help to get into shape but this weight loss drug also helps prevent health problems caused by obesity. Work of Acomplia Acomplia weight loss drug not only reduce obesity but this weight loss drug is also used to quit smoking. For best and fast results, it's advised that weight loss drug Acomplia should be taken on a regular basis. For maximum results, Acomplia weight loss drug should be supplemented with healthy diet and regular exercise. Acomplia weight loss drug also helps combating alcohol. Acomplia weight
Bone marrow cells produce nerve growth factor and promote angiogenesis around transplanted islets.CONCLUSION: Bone marrow cells produce NGF and promote angiogenesis. Islet co-transplantation with bone marrow is associated with improvement of islet graft function.
PMID: 20222164 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Microalbuminuria in hepatitis C-genotype 4: Effect of pegylated interferon and ribavirin.CONCLUSION: HCV affected the development of microalbuminuria independent of diabetes or cryoglobulinemia. Combination therapy of pegylated interferon-ribavirin had a positive effect in reducing microalbuminuria.
PMID: 20222166 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)In vitro activity of tigecycline against patient isolates collected during phase 3 clinical trials for diabetic foot infectionsAbstract: The in vitro activity of tigecycline and comparative antimicrobial agents was evaluated against 1828 primary baseline pathogens isolated from 844 patients enrolled in the phase 3 clinical trials investigating the efficacy of tigecycline in diabetic foot infection (DFI). The trials were global, enrolling patients in 30 countries. Tigecycline was active against the most prevalent pathogens in DFI, including Gram-positive and Gram-negative isolates of both aerobic and anaerobic bacteria with 95% of MICs ?2 ?g/mL for the entire collection. The spectrum of activity of tigecycline included important pathogens for DFI, such as Staphylococcus aureus, Enterococcus faecalis, Streptococcus agalactiae, Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae, and Bacteroides fragilis...Antepartum and Intrapartum Risk Factors for Neonatal Encephalopathy at TermIn conclusion, 44% of cases of NE following term deliveries can be attributed to a combination of antepartum and intrapartum variables.[...]© Thieme Medical PublishersGet connected:Table of contents | Abstract | Full text (Source: American Journal of Perinatology)Carrot-And-Stick Health Plans Aim to Cut CostsKaiser Health News article tells how workers at a Portland, Ore., steel mill soon will be able to pick a new type of insurance that offers free care for some illnesses, such as diabetes or depression, but requires hefty extra fees for treatments deemed overused, including knee replacements, hysterectomies and heart bypass surgery. (Source: News stories via the Rural Assistance Center)Chapter 7 - ZygomycosisThis article describes the general characteristics of pulmonary zygomycosis, emphasizing laboratory diagnosis, and illustrates the morphology of some lesions. (Source: Jornal Brasileiro de Pneumologia)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Acute renal dysfunction following hip fractureAbstract: We investigated the incidence, risk factors and outcome of acute renal dysfunction (ARD) in patients with a fractured neck of femur.170 consecutive patients were prospectively included in the Scottish Hip Fracture Audit database and retrospectively analysed. Historically, lack of consensus definition has hindered accurate reporting of ARD. ARD was defined using the ?RIFLE? criteria.27 patients (16%) developed ARD. Risk factors were male sex, vascular disease, hypertension, diabetes, chronic kidney disease and pre-morbid use of nephrotoxic medications (p (Source: Injury)Switch to insulin therapy does not reduce rate of UTIs in Type 2 diabeticsThere is no evidence that switching from oral treatment to insulin therapy reduces the high rate of urinary tract infections in patients with Type 2 diabetes, say researchers. (Source: MedWire News - Diabetes)Better to Start Metformin Early (CME/CE, with audio)For newly diagnosed type 2 diabetes, waiting until lifestyle measures fail before starting metformin may jeopardize the long-term efficacy of the drug, a large clinical database analysis showed. (Source: MedPage Today Primary Care)Mimetics of hormetic agents: stress-resistance triggers.Authors: Sonneborn JS
Mimetics of hormetic agents offer a novel approach to adjust dose to minimize the risk of toxic response, and maximize the benefit of induction of at least partial physiological conditioning. Nature selected and preserved those organisms and triggers that promote tolerance to stress. The induced tolerance can serve to resist that challenge and can repair previous age, disease, and trauma damage as well to provide a more youthful response to other stresses. The associated physiological conditioning may include youthful restoration of DNA repair, resistance to oxidizing pollutants, protein structure and function repair, improved immunity, tissue remodeling, adjustments in central and peripheral nervous systems, and altered metabolism. By elucidating common pathways ...Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes(Source: BMJ Online First)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Acute exacerbation impairs endothelial function in patients with chronic obstructive pulmonary disease.CONCLUSION: Acute COPD exacerbation is associated with worsening endothelial function, increasing the risk for cardiovascular morbidity.
PMID: 20215835 [PubMed - as supplied by publisher] (Source: Turk Kardiyoloji Dernegi arsivi)Survey: Employers Plan To Shift More Health Costs To WorkersNews outlets report on new trends in health insurance for employers. The Washington Post: "Most big employers plan to shift a larger share of health-care costs to their workers next year, according to a survey to be released Thursday. ... (Source: Diabetes News From Medical News Today)Growth Of Chronic Kidney Disease Highlights Need For Early Detection, Greater Knowledge Of Treatment OptionsAs the incidence of diabetes and hypertension continues to grow worldwide - and increasing numbers of patients progressing to kidney disease and kidney failure place a financial strain on public health systems - the need for early patient education about kidney disease and treatment options, including home-based treatments, has become critical... (Source: Hypertension News From Medical News Today)Growth Of Chronic Kidney Disease Highlights Need For Early Detection, Greater Knowledge Of Treatment OptionsAs the incidence of diabetes and hypertension continues to grow worldwide - and increasing numbers of patients progressing to kidney disease and kidney failure place a financial strain on public health systems - the need for early patient education about kidney disease and treatment options, including home-based treatments, has become critical. More than 240 million people have diabetes and this figure is projected to rise to 380 million by 20251. In the United States alone, 17.9 million have been diagnosed with diabetes resulting in medical and indirect costs (e.g... (Source: Health News from Medical News Today)Access Pharmaceuticals Reports Significant Oral Bioavailability Of Cobalamin(TM) Oral Insulin In Additional StudiesACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP) announced that it has received reports of significant bioavailability of orally delivered insulin in two independently-conducted animal studies. The studies, which confirm earlier findings, were performed as part of on-going work with commercial collaborators that are evaluating Access' Cobalamin? Oral Drug Delivery Technology... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>New Alterations Found In Young Adults With Type 2 DiabetesDiet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A study at the Institute for Research in Biomedicine (IRB Barcelona) and Trinity College in Dublin demonstrates that obese subjects between 18 and 25 years of age carry mitochondrial proteins and genes that work abnormally and that these anomalies contribute to generating insulin resistance and a reduced response to physical exercise... (Source: Health News from Medical News Today)Access Pharmaceuticals Reports Significant Oral Bioavailability Of Cobalamin(TM) Oral Insulin In Additional StudiesACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP) announced that it has received reports of significant bioavailability of orally delivered insulin in two independently-conducted animal studies. The studies, which confirm earlier findings, were performed as part of on-going work with commercial collaborators that are evaluating Access' Cobalamin? Oral Drug Delivery Technology... (Source: Diabetes News From Medical News Today)New Alterations Found In Young Adults With Type 2 DiabetesDiet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young... (Source: Diabetes News From Medical News Today)Africa: Non Communicable Diseases Recognised As Major Cause of Premature Deaths in Developing CountriesNon-communicable diseases (NCDs), such as heart diseases, diabetes, cancer and respiratory diseases account for approximately 60 percent of deaths worldwide. (Source: AllAfrica News: Health and Medicine)Australian Health Insurer NIB and Navigenics Team Up to Offer Cut-Rate Genetic Testing to NIB CustomersAustralian patients are using an American clinical pathology laboratory for their genetic testing needs
It?s a half-price sale of genetic clinical laboratory tests for 5,000 customers of Australian health insurer NIB. NIB wants to encourage its beneficiaries to screen themselves to identify their genetic tendencies for such conditions as heart disease, diabetes, some cancers, and [...] (Source: Dark Daily)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Epidemic of Vitamin D deficiency sweeping the world(NaturalNews) There is an epidemic of vitamin D deficiency sweeping across our modern world, and it's an epidemic of such depth and seriousness that it makes the H1N1 swine flu epidemic look like a case of the sniffles by comparison. Vitamin D deficiency is not only alarmingly widespread, it's also a root cause of many other serious diseases such as cancer, diabetes, osteoporosis and heart disease.A new study published in the March, 2010 issue of the Journal of Clinical Endocrinology and Metabolism found that a jaw-dropping 59 percent of the population is vitamin D deficient. In addition, nearly 25 percent of the study subjects were found to have extremely low levels of vitamin D.Lead author of the study, Dr. Richard Kremer at the McGill University Health Center, said "Abnormal levels of v...Vitamin D Improves Insulin Sensitivity, Helps Prevent Diabetes(NaturalNews) High-dose vitamin D supplements may help increase the body's sensitivity to the blood sugar-regulating hormone insulin, thus reducing the risk of diabetes, researchers have found.Insulin resistance (or insensitivity) occurs when the body's tissues stop responding as strongly to the presence of insulin. As a consequence, the cells uptake less sugar from the bloodstream, producing the elevated glucose levels characteristic of diabetes. In the current study, conducted by researchers from Massey University and published in the British Journal of Nutrition, researchers randomly assigned 81 South Asian women between the ages of 23 and 68 to take either a placebo or 4,000 IU of vitamin D once per day. All participants suffered from insulin sensitivity at the start of the study, but ...Exercising just got easier for busy people, study shows(McMaster University) Researchers have found that interval training does not have to be "all out" to be effective in helping reduce the risk of such diseases at Type 2 diabetes. (Source: EurekAlert! - Social and Behavioral Science)Asymmetric Large-for-Gestational-Age Infants of Type 1 Diabetic Women: Morbidity and Abdominal GrowthAmer J PerinatolDOI: 10.1055/s-0030-1249362ABSTRACTWe sought to examine neonatal morbidity in four groups of offspring (asymmetric large for gestational age [LGA], symmetric LGA, asymmetric non-LGA, symmetric non-LGA) exposed in utero to maternal type 1 diabetes, and the association between rate of fetal abdominal circumference growth and asymmetric LGA. We performed a secondary analysis of 302 singleton pregnancies. Neonatal morbidity (respiratory distress syndrome, polycythemia, hypoglycemia, hyperbilirubinemia, acidosis, and composite morbidity [any of the five]) was assessed. Serial ultrasound examinations after 20 weeks' gestation were available for 35 fetuses. Logistic regression and general linear mixed modeling were used for analysis. Asymmetric LGA infants had 3.5-, 2.2-, and 3.2-...Diabetes Link to Eating DisordersDiabetics, under the gun to better manage their disease by controlling their food intake and weight, may find themselves in the sticky wicket of needing treatment that makes them hungry, researchers said. (Source: Disabled World)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Glycemic index diet: A helpful tool for diabetes?Some people with diabetes use the glycemic index (GI) as a guide in selecting foods. (Source: MayoClinic.com - Ask a Specialist)Diabetes and Cognitive Decline: Investigating the Potential Influence of Factors Related to Health DisparitiesDiscussion: Findings suggest that factors related to health disparities may influence cognitive outcomes among older adults with diabetes. (Source: Journal of Aging and Health)[Viewpoint] The role of academic health science systems in the transformation of medicineThe challenges facing the health of communities around the world are unprecedented, and the data are all too familiar. For 5 billion people living in developing countries, environmental factors and inadequacies in hygiene, economic development, and health-care access are the main causes of shortened life expectancies. Improvements in health status, including reductions in infant mortality and declining incidence of infectious diseases, are being met by the new epidemics of obesity, diabetes mellitus, and cardiovascular disease. (Source: LANCET)Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats.Conclusion:
Excessive dietary fat and/or increased levels of luminal bile juice, but not genetic obesity, are responsible for the increase in small intestinal permeability resulting from the suppression of TJ protein expression. (Source: Nutrition & Metabolism)Use of pegaptanib for recurrent and non-clearing vitreous haemorrhage in proliferative diabetic retinopathyAuthors: D Hornan, N Edmeades, R Krishnan, J Khan
& J Lochhead (Source: Eye)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY)Conclusion:
Mutations in INS can be a rare cause of MODY and we conclude that screening for mutations in INS should be recommended in MODYX patients. (Source: BMC Medical Genetics - Latest articles)Oxidative and Nitrosative Stress and Progression of Diabetic Nephropathy in Type 2 DiabetesAm J Nephrol 2010;31:342–352 (DOI:10.1159/000297290) (Source: Karger Publishers)Big first trimester weight gain ups diabetes riskNEW YORK (Reuters Health) - Women who gain weight too quickly during the first three months of pregnancy are more prone to develop pregnancy-related diabetes, new research shows. (Source: Reuters: Health)Comorbid Diabetes and Depression Increase Dementia RiskPatients with diabetes and major depression have a markedly increased risk of developing dementia compared with their counterparts with diabetes alone. Medscape Medical News (Source: Medscape Today Headlines)FDA Says No "Clear Connection" Between Bisphosphonate Use and Femur Fracture RiskFDA Says No "Clear Connection" Between Bisphosphonates, Femur Fracture Risk Medscape Medical News (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Cholesterol, Diabetes Medications Top List of Prescription Drug Expenses for Medicare RecipientsMetabolic agents make up nearly one quarter of all purchases by those aged 65 years and older. Medscape Medical News (Source: Medscape Today Headlines)Long-Acting Insulin Analogs May up Risk of Diabetic Ketoacidosis in ChildrenUse of insulin glargine or detemir rather than NPH insulin does not reduce the risk of ketoacidosis in children and adolescents with type 1 diabetes, and in fact may increase the risk, a new study shows. Reuters Health Information (Source: Medscape Diabetes Headlines)Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE studyThis study provides evidence that calls for prospective evaluation of the roles of transfusion, iron chelation, and hydroxyurea therapy in TI patients. (Source: Blood)Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases, or Diabetes (R01)Funding Opportunity Number: RFA-DK-10-004 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: Food and NutritionHealthCFDA Number: 93.847Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationNonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher educationPrivate instit...World Kidney Day PodcastThe focus on diabetic kidney disease for World Kidney Day 2010 brings awareness of the magnitude of the problem and ramifications for global health for people with diabetes and kidney disease. It is therefore time to act and act urgently. It is time for strategies that prevent diabetes and its sequelae. It is time for programs for health care workers to diagnose and treat people with diabetic kidney disease. It is time for governments to pass legislation to enable the diabetes pandemic to be controlled. After all, diabetic kidney disease, like the epidemics of infectious diseases that have long dominated public health agendas, is potentially preventable. Indeed, March 11, 2010 is time to act on diabetic kidney disease and to commit to sustaining that action long after World Kidney Day.
Li...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>2009 H1N1 Influenza and its Impact on People with Chronic Medical Conditions: Questions and AnswersThe January 12, 2010 National Influenza Vaccination Week Webinar featured Dr. Nicole Lurie with the US Department of Health and Human Services; Dr. Anthony Fiore with Centers for Disease Control and Prevention; Dr. Otis Webb Brawley with American Cancer Society; Christine Tobin with American Diabetes Association; and Mary Partridge with the American Lung Association. (Source: PandemicFlu.gov RSS Feed for News Releases)Metabolic Meds Top Medicare Drug SpendingMetabolic drugs (MedPage Today) -- namely cholesterol and diabetes meds -- account for the greatest Medicare prescription expenses, researchers say. (Source: MedPage Today Public Health)Foods high in meat and fat confer increased risk for diabetes in all ethnic groupsFoods high in meat and fat appear to confer an increased risk for diabetes in all ethnic groups, whereas the effects of other dietary patterns vary by gender and ethnicity, say US researchers. (Source: MedWire News - Diabetes)Descending Necrotising Mediastinitis, A Fatal Disease to Keep in MindWe report an unusual case of primary retropharyngeal abscess complicated by descending necrotising mediastinitis and bilateral empyema in a 56-year-old diabetic man. The diagnosis of descending necrotising mediastinitis (DNM) was established by the characteristic findings on computed tomography. The patient was treated by cervicotomy and staged bilateral posterolateral thoracotomy. (Source: Heart, Lung & Circulation)Impact of Chronic Kidney Disease on Platelet Function Profiles in Diabetes Mellitus Patients With Coronary Artery Disease Taking Dual Antiplatelet TherapyConclusions: In DM patients with coronary artery disease taking maintenance aspirin and clopidogrel therapy, impaired renal function is associated with reduced clopidogrel-induced antiplatelet effects and a greater prevalence of HPPR. (Source: Journal of the American College of Cardiology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Determinants of Coronary Calcium Conversion Among Patients With a Normal Coronary Calcium Scan: What Is the ?Warranty Period? for Remaining Normal?Conclusions: Among individuals with CAC = 0, conversion to CAC >0 is nonlinear and occurs at low frequency before 4 years. No clinical factor seems to mandate earlier repeat CAC scanning. (Source: Journal of the American College of Cardiology)Single and unhappily married men are at 64% higher risk of dying from strokeMen who were single in the 1960s were 64% more likely to suffer a fatal stroke over the next three decades than their married counterparts.The risk of fatal stroke was also 64% higher in men who reported dissatisfaction with their marriages than in men who rated their marriages as successful.That figure is comparable to the risk of fatal stroke faced by men with diabetes.References:Single Men Have Higher Risk of Stroke. WebMD.Image source: CT scan slice of the brain showing a right-hemispheric ischemic stroke (left side of image). Wikipedia, GNU Free Documentation License.
Posted at Clinical Cases and Images. Stay updated and subscribe, follow on Twitter and Buzz, and connect on Facebook. (Source: Clinical Cases and Images)Medical care costs among patients with established cardiovascular disease.CONCLUSIONS: The economic burden of providing care to patients with CVD may be substantially greater than current American Heart Association estimates. Although several comorbid conditions undoubtedly contribute to these costs, avoidance of secondary CVD hospitalization may be the key to substantially reducing healthcare consumption.
PMID: 20205493 [PubMed - in process] (Source: The American Journal of Managed Care)Diabetic kidney disease: act now or pay later.Authors: Atkins RC, Zimmet P
PMID: 20213919 [PubMed - in process] (Source: American Journal of Nephrology)New cholesterol drug testedConclusion
This is an important and well-conducted trial, which has demonstrated the potential of a drug, eprotirome, to lower cholesterol levels. However, conclusions about the effects of this drug should not be made too prematurely and much further research is needed:
So far, use of the drug alone has not been compared to statin treatment. In this trial eprotirome or inactive placebo was only ever given in addition to people?s long-term statins. Therefore no comparison of cholesterol-lowering effect of each of the treatments alone can be made.
Only a small number of people were included in the trial: 47 on the 25microgram dose, 46 on 50micrograms, and 44 on the 100microgram dose of eprotirome. These groups of participants are too small to draw any conclusions on the safety or eff...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Agency For Healthcare Research And Quality News And Numbers: High Cholesterol, Diabetes Lead Drug Spending For The ElderlyPurchases of cholesterol and diabetes prescription drugs by elderly Medicare beneficiaries reached nearly $19 billion in 2007 - about one-fourth of the approximately $82 billion spent for medications for the elderly, according to the latest AHRQ News and Numbers... (Source: Cholesterol News From Medical News Today)The American Diabetes Association Encourages Community Organizations To Join The Movement To Stop DiabetesThe American Diabetes Association announced today their efforts to further engage community organizations across the country in raising awareness about the seriousness of diabetes and its complications through the Association's Stop Diabetes movement. The American Diabetes Association is rolling out a Stop Diabetes Community Outreach Toolkit to help community and faith-based organizations, health clinics, libraries, hospitals, fraternal groups and corporations raise awareness of diabetes risk factors among their constituents... (Source: Health News from Medical News Today)Agency For Healthcare Research And Quality News And Numbers: High Cholesterol, Diabetes Lead Drug Spending For The ElderlyPurchases of cholesterol and diabetes prescription drugs by elderly Medicare beneficiaries reached nearly $19 billion in 2007 - about one-fourth of the approximately $82 billion spent for medications for the elderly, according to the latest AHRQ News and Numbers. Metabolic drugs, which are used to lower cholesterol levels, keep diabetes under control and for weight and thyroid problems, topped the list of the five leading categories of drugs purchased by the elderly... (Source: Health News from Medical News Today)Glycated Hemoglobin Tests See Increasing UseGlycated hemoglobin (HbA1c) testing is one of the success stories of point-of-care diagnostics, and an area that will experience higher growth rates than other POC tests as a result of expert recommendations, new cases and booming mail-in test sales, according to the new report "Point-of-care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads," by healthcare market research publisher Kalorama Information. The test measures glucose attached to the blood protein hemoglobin, a well-established analyte related to the long-term evaluation of blood sugar control... (Source: Health News from Medical News Today)The American Diabetes Association Encourages Community Organizations To Join The Movement To Stop DiabetesThe American Diabetes Association announced today their efforts to further engage community organizations across the country in raising awareness about the seriousness of diabetes and its complications through the Association's Stop Diabetes movement... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Glycated Hemoglobin Tests See Increasing UseGlycated hemoglobin (HbA1c) testing is one of the success stories of point-of-care diagnostics, and an area that will experience higher growth rates than other POC tests as a result of expert recommendations, new cases and booming mail-in test sales, according to the new report "Point-of-care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads," by healthcare market rese... (Source: Diabetes News From Medical News Today)Recent Studies Link Obesity To Food AllergiesFirst Lady Michelle Obama's "Let's Move" Campaign tells us that about 32 percent of children and teens (or 25 million) are obese or overweight. It revealed those extra pounds put them at greater risk of developing debilitating and costly diseases including diabetes, high blood pressure and high cholesterol and may also cause them to lead a two to five year shorter life than their parents... (Source: Health News from Medical News Today)Recent Studies Link Obesity To Food AllergiesFirst Lady Michelle Obama's "Let's Move" Campaign tells us that about 32 percent of children and teens (or 25 million) are obese or overweight. It revealed those extra pounds put them at greater risk of developing debilitating and costly diseases including diabetes, high blood pressure and high cholesterol and may also cause them to lead a two to five year shorter life than their parents... (Source: Allergy News From Medical News Today)No mortality benefit in reducing HbA1c below 9%There is little to gain in terms of reduced mortality from continually lowering HbA1c targets in patients with type 2 diabetes, a Dutch study has concluded. (Source: Pulse)Frequent napping linked to increased risk of type 2 diabetes in older adultsA study shows that frequent napping is associated with an elevated prevalence of type 2 diabetes and impaired fasting glucose in an older Chinese population. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Cardiac Catheterizations: Too Many Performed?Title: Cardiac Catheterizations: Too Many Performed?Category: Health NewsCreated: 3/11/2010 10:14:00 AMLast Editorial Review: 3/11/2010 10:14:51 AM (Source: MedicineNet Diabetes General)Glycemic index diet: A helpful tool for diabetes?Some people with diabetes use the glycemic index (GI) as a guide in selecting foods. (Source: MayoClinic.com Full Feed)New alterations found in young adults with type 2 diabetes(Institute for Research in Biomedicine (IRB Barcelona)) Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A study at the IRB Barcelona and Trinity College in Dublin demonstrates that obese subjects between 18 and 25 years of age carry mitochondrial proteins and genes that work abnormally and that these anomalies contribute to generating insulin resistance and a reduced response to physical exercise. (Source: EurekAlert! - Medicine and Health)Insurers Test Health Plans that Stress Patient ChoicesWorkers at a Portland, Ore., steel mill soon will be able to pick a new type of insurance that offers free care for some illnesses, such as diabetes or depression, but requires hefty extra fees for treatments deemed overused, including knee replacements, hysterectomies and heart bypass surgery. (Source: RWJF News Digest - Quality/Equality)New alterations found in young adults with type 2 diabetesDiet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A new study demonstrates that obese subjects between 18 and 25 years of age carry mitochondrial proteins and genes that work abnormally and that these anomalies contribute to generating insulin resistance and a reduced response to physical exercise. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Diabetes' link to eating disorders explored(Medical College of Georgia) Diabetics, under the gun to better manage their disease by controlling their food intake and weight, may find themselves in the sticky wicket of needing treatment that makes them hungry, researchers said. (Source: EurekAlert! - Biology)Body's anticipation of a meal can be a diabetes risk factor(Duke University Medical Center) Alterations in our response to the taste or smell of food may be another culprit responsible for Type 2 diabetes, according to scientists at Duke University Medical Center who have identified the specific mechanism in human specimens and in mice. (Source: EurekAlert! - Medicine and Health)Depression plus diabetes may = dementiaSEATTLE, March 10 (UPI) -- Diabetes combined with depression increases dementia risk, University of Washington researchers found. (Source: Health News - UPI.com)Measurement of Adiponectin Production from Differentiated Metabolic Stem CellsHorm Metab ResDOI: 10.1055/s-0030-1248304AbstractTo treat metabolic syndrome, fat tissue dysfunction should be corrected rather than controlling conventional risk factors such as hypertension, dyslipidemia, and diabetes mellitus. For this purpose, accumulating evidence suggests increasing plasma adiponectin levels can be a key treatment strategy, especially in setting of food or drug selection. Here we report that adipocyte precursors obtained from several sites of fat tissue, which we call Metabolic Stem Cells (MSC), could be used as a novel screening system to identify adiponectin enhancing drugs or food for individual patients. MSC were prepared from fat tissues collected from 29 patients. They were differentiated in cultures into mature adipocytes. The time course of adiponectin produc...ZenBio Licenses An Important Cell Line From Harvard To Drive Metabolic Disease ResearchZenBio announce that they will be a commercial source for the popular murine 3T3-L1 cell line, which has been fundamental in metabolic disease research for 30 years. Originally derived from Swiss mouse embryo tissue by Dr. Howard Green of the Department of Cell Biology at Harvard Medical School, the 3T3-L1 system has been pivotal in advancing the understanding of basic cellular mechanisms associated with diabetes, obesity and other related disorders... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>An observational study of type 2 diabetes within a large Australian tertiary hospital pediatric diabetes serviceConclusions: At present, T2DM in youth remains a low burden on our services. Patients with this diagnosis, however, have significant problems that present a major challenge to the development of effective management strategies. (Source: Pediatric Diabetes)Comparison of Humalog Mix 50 with human insulin Mix 30 in type 2 diabetes patients during RamadanConclusion: Changing to humalog Mix 50 during Ramadan resulted in improvement in glycaemic control without increasing the incidence of hypoglycaemia. (Source: International Journal of Clinical Practice)Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) [ggr]Obesity is one of the predisposing factors for the development of overt Type 2 diabetes (T2D). T2D is caused by a combination of insulin resistance and [bgr]-cell failure and can be treated with insulin sensitizing drugs that target the nuclear receptor peroxisome proliferator-activated receptor (PPAR) [ggr]. Extracts of elderflowers (Sambucus nigra) have been found to activate PPAR[ggr] and to stimulate insulin-dependent glucose uptake suggesting that they have a potential use in the prevention and/or treatment of insulin resistance. Bioassay-guided chromatographic fractionation of a methanol extract of elderflowers resulted in the identification of two well-known PPAR[ggr] agonists; [agr]-linolenic acid and linoleic acid as well as the flavanone naringenin. Naringenin was found to activa...Varying recurrence rates and risk factors associated with different definitions of local recurrence in patients with surgically resected, stage I nonsmall cell lung cancerThe objective of this study was to examine the effects of different definitions of local recurrence on the reported patterns of failure and associated risk factors in patients who undergo potentially curative resection for stage I nonsmall cell lung cancer (NSCLC).The study included 306 consecutive patients who were treated from 2000 to 2005 without radiotherapy. Local recurrence was defined either as "radiation" (r-LR) (according to previously defined postoperative radiotherapy fields), including the bronchial stump, staple line, ipsilateral hilum, and ipsilateral mediastinum; or as "comprehensive" (c-LR), including the same sites plus the ipsilateral lung and contralateral mediastinal and hilar lymph nodes. All recurrences that were not classified as "local" were considered to be distal....NHS Diabetes publishes new guidelines on the management of patients with diabetesSource: NHS Diabetes
Area: News
NHS Diabetes have published a range of new publications at the Diabetes UK Annual Professional Conference (please see links below for access to the guidelines):
. Hospital management of hypoglycaemia in adults with diabetes mellitus . Joint British Diabetes Societies Inpatient Care Group: The Management of Diabetic Ketoacidosis in Adults . Safe and Effective use of Insulin in Hospitalised Patients . Emotional and Psychological Support and Care in Diabetes Report from the emotional and psychological support working group of NHS Diabetes and Diabetes UK . Self monitoring of blood glucose in non-insulin-treated Type 2 diabetes . Diabetes - put your feet first. Top tips: foot care information for people with diabetes (So...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>No association between thiazolidinedione exposure and DMEExposure to thiazolidinediones is not associated with increased risk for diabetic macular edema in patients with Type 2 diabetes, suggest study results. (Source: MedWire News - Diabetes)Thiazolidinediones Not Linked to Diabetic Macular EdemaIn patients with type 2 diabetes, thiazolidinedione exposure is not associated with an increased risk
of diabetic macular edema. In addition, an intravitreous dexamethasone drug delivery system shows promise in the
treatment of persistent diabetic macular edema, according to research published in the March issue of the Archives
of Ophthalmology. (Source: Modern Medicine)In Vitro Potential of Ascophyllum nodosum Phenolic Antioxidant-Mediated α-Glucosidase and α-Amylase InhibitionThis study suggests a nutraceutical potential of A. nodosum based on phytochemical antioxidant and antihyperglycemia activities. (Source: Journal of Food Science)Diamyd Medical: Diamyd US Phase III Study Well Under WayDiamyd Medical (STO:DIAMB)(Pink Sheets:DMYDY) announces today that one hundred study participants have been included in the ongoing US Phase III study, DiaPrevent. The global Phase III program with the company's lead drug candidate Diamyd® has thereby enrolled more than 430 children newly diagnosed with type 1 diabetes in Europe and the USA. One hundred patients are now enrolled in the company's US Phase III study called DiaPrevent at 33 diabetes centers throughout the USA and more sites will be added... (Source: Health News from Medical News Today)Diamyd Medical: Diamyd US Phase III Study Well Under WayDiamyd Medical (STO:DIAMB)(Pink Sheets:DMYDY) announces today that one hundred study participants have been included in the ongoing US Phase III study, DiaPrevent. The global Phase III program with the company's lead drug candidate Diamyd® has thereby enrolled more than 430 children newly diagnosed with type 1 diabetes in Europe and the USA... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Treatment of Gestational Diabetes Does Not Affect Childhood BMIWhile treatment of gestational diabetes markedly reduces macrosomia at birth, it does not reduce the infant's risk of a high body mass index (BMI) in early childhood. Reuters Health Information (Source: Medscape Medical News Headlines)Thiazolidinediones Don't Cause Macular Edema: StudyThiazolidinediones don't seem to cause macular edema in type 2 diabetics, the ACCORD Study Group reports. Reuters Health Information (Source: Medscape Medical News Headlines)Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases, or Diabetes (R01)Request for Applications from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP-C/EBP{alpha} in human umbilical vein endothelial cells from gestational diabetesConclusion
The hCHOP–C/EBP complex down-regulates SLC29A1 expression in an NO-dependent manner in HUVECs from gestational diabetes. (Source: Cardiovascular Research)18F-fluorodeoxyglucose positron emission tomography immediately after chemoradiotherapy predicts prognosis in patients with locoregional postoperative recurrent esophageal cancerConclusions FDG-PET performed even <7 days after chemoradiotherapy predicts prognosis in patients with postoperative recurrent esophageal
cancer.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10147-010-0044-yAuthors
Keiichi Jingu, Tohoku University School of Medicine Department of Radiation Oncology 1-1 Seiryo-machi, Aoba-ku Sendai 980-8574 JapanTomohiro Kaneta, Tohoku University School of Medicine Department of Diagnostic Radiology Sendai JapanKenji Nemoto, Yamagata University School of Medicine Department of Radiation Oncology Yamagata JapanKen Takeda, Tohoku University School of Medicine Department of Radiation Oncology 1-1 Seiryo-machi, Aoba-ku Sendai 980-8574 JapanYoshihiro Ogawa, Tohoku University School of Medicine Department of Rad...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Serum Cyfra 21.1 and galectin-3 protein levels in relation to immunohistochemical cytokeratin 19 and galectin-3 expression in patients with thyroid tumorsConclusions While CK19 and gal-3 are accurate as tissue markers, their serum levels could not be used as reliable markers for identification
of thyroid malignancy or in thyroid cancer follow-up. On the other hand, a tendency toward higher serum levels of Cyfra 21.1
in the small number of PDTC patients examined adds weight to previous reports postulating a role for cytokeratins in predicting
a high degree of malignancy.
Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00432-010-0838-3Authors
Tijana I?i?, University of Belgrade Institute for the Application of Nuclear Energy, INEP Banatska 31b 11080 Zemun, Belgrade SerbiaSvetlana Savin, University of Belgrade Institute for the Application of Nuclear Energy, INEP Banatska 31b 11080 Zemun, Belgrade Ser...L-Arginine in pregnant scleroderma patientsAbstract Systemic sclerosis (SSc) pregnant women show a high frequency of premature births and occurrence of renal crisis. Some evidences
showed the role of L-arginine in the prevention and treatment of preeclampsia. Here, we report our experience on the effect of L-arginine treatment in four consecutive SSc pregnant women. Two patients, who have planned the pregnancy, were treated with
oral L-arginine; both delivered healthy babies without any prenatal complications. The other two, with high risk of pregnancy complications
because of severe lung involvement and type 1 diabetes, respectively, underwent i.v. L-arginine: patient 3 had a premature delivery of a 2-kg healthy baby, while patient 4 developed preeclampsia and, at the 28th
week, delivered a 1,050-g girl. The neonate...Late mortality in pediatric patients with craniopharyngiomaAbstract Ten year survival rates for patients with craniopharyngioma vary from 24 to 100%. A review of the database of all children
diagnosed with craniopharyngioma in British Columbia (BC) revealed that several patients died >10 years after diagnosis. This
retrospective study investigates the causes and timing of deaths and reports the overall survival in this population based
group of patients. A chart review was conducted on all patients aged <17 years, diagnosed in BC with craniopharyngioma between
1967 and 2003. Imaging studies were reviewed by a neuroradiologist. All deaths in the province are reported to a central agency,
which allowed identification of patients who died after being lost to clinical follow up. Forty-one patients were identified
with ...Entering and Exiting the Medicare Part D Coverage Gap: Role of Comorbidities and DemographicsCONCLUSIONS Certain chronically ill MAPD enrollees are at high risk of gap entry and exposure to unsubsidized medication costs. Clinically
vulnerable populations should be counseled on how to best manage costs through drug substitution or discontinuation of specific,
non-essential medications.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s11606-010-1300-6Authors
Susan L. Ettner, David Geffen School of Medicine at UCLA Division of General Internal Medicine and Health Services Research, Department of Medicine 911 Broxton Plaza Los Angeles CA 90024 USANeil Steers, David Geffen School of Medicine at UCLA Division of General Internal Medicine and Health Services Research, Department of Medicine 911 Broxton Plaza Los Angeles CA 90024 USAO. Kenrik Duru,...Pioglitazone modulates tumor cell metabolism and proliferation in multicellular tumor spheroidsAbstract The anti-diabetic thiazolidinedione compound pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, and
selective cyclooxygenase-2 inhibitors are clinically used in patients with advanced malignancies. Several previously published
in vivo and in vitro studies showed growth inhibitory effects on different cancer cell lines. However, the underlying mechanisms
are fairly unclear. Here, we analyzed the effects of pioglitazone in combination with other drugs in a three-dimensional multicellular
tumor spheroid culture system (MCTS) generated from the two prostate carcinoma cell lines PC3 and LNCaP. As expected, pioglitazone
also inhibited tumor cell proliferation in the MCTS system. Further studies revealed that pioglitazone lowered the pH of the
cult...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Diabetes and cardiovascular diseaseAbstract Compelling evidence has been accumulating that hyperglycemia is independently related with excessive morbidity and mortality
in cardiovascular disease (CVD) involving all components of the ?gluco-triade?, i.e., HbA1c, fasting plasma glucose, and postprandial
or postload plasma glucose. Today's policy for blood glucose-lowering therapy must be ?reach and maintain glycemic goals safely
and gently.? All available drug options provide a (placebo substracted) HbA1c decrease of around 1%. Due to the often much
higher demand for lowering HbA1c, double combinations and even triple therapies are necessary. Avoiding side effects, especially
hypoglycemia and too much weight gain, seems to be a priority of today's blood glucose-lowering therapy. The effectiveness
of b...The ApoB/ApoA1 Ratio is Associated with Metabolic Syndrome and its Components in a Chinese PopulationIn this study, we assessed whether the apolipoprotein B/apolipoprotein A1 ratio (ApoB/ApoA1) is related to metabolic syndrome
(MS) and its components in an urban Chinese population. A total of 709 community residents were enrolled. Metabolic syndrome
was defined according to the International Diabetes Federation definition in 2005. The high ApoB/ApoA1 group was defined as
the gender-specific upper quartile of the ApoB/ApoA1 ratio. Insulin resistance (IR) was defined as the upper quartile of Homa-IR.
The ApoB/ApoA1 ratio was significantly higher in subjects with MS, compared to those without (p?<?0.05). After adjusting for age and gender, subjects with MS (odds ratio [OR]?=?3.5) or IR (OR?=?2.3) were more likely to
be in the high ApoB/ApoA1 group. The ApoB/ApoA1 ratio in...Type 2 diabetes impairs pulmonary function in morbidly obese women: a case?control studyConclusions/interpretation The presence of diabetes and the degree of glycaemic control are related to respiratory function impairment in morbidly obese
women. Therefore, the impact of type 2 diabetes on pulmonary function should be taken into consideration by those providing
care for obese people.
Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-010-1700-5Authors
A. Lecube, Institut de Recerca Hospital Universitari Vall d?Hebron CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Diabetes and Metabolism Research Unit Passeig Vall d?Hebron, 119-129 08035 Barcelona SpainG. Sampol, Institut de Recerca Hospital Universitari Vall d?Hebron CIBER Enfermedades Respiratorias (CIBERES), Instituto de ...Overexpression of the orphan receptor Nur77 alters glucose metabolism in rat muscle cells and rat muscle in vivoConclusions/interpretation Our data provide compelling evidence that NUR77 is a functional regulator of glucose metabolism in skeletal muscle in vivo.
Importantly, the diminished content in muscle of obese insulin-resistant men suggests that it might be a potential therapeutic
target for the treatment of dysregulated glucose metabolism.
Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-010-1703-2Authors
T. Kanzleiter, Garvan Institute of Medical Research Diabetes and Obesity Research Program 384 Victoria Street, Darlinghurst Sydney NSW 2010 AustraliaE. Preston, Garvan Institute of Medical Research Diabetes and Obesity Research Program 384 Victoria Street, Darlinghurst Sydney NSW 2010 AustraliaD. Wilks, Garvan Institute of Medical Research Diabetes and O...Determinants of glucose control in patients with chronic pancreatitisConclusions/interpretation Hyperglycaemia in CP patients is associated with reduced beta cell area. However, reduced beta cell area does not predict
the development of diabetes, suggesting that other factors are more important determinants of alterations in glucose metabolism
in patients with CP.
Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-010-1705-0Authors
H. Schrader, Ruhr-University Bochum Department of Medicine I, St Josef-Hospital Gudrunstr. 56 44791 Bochum GermanyB. A. Menge, Ruhr-University Bochum Department of Medicine I, St Josef-Hospital Gudrunstr. 56 44791 Bochum GermanyC. Zeidler, Ruhr-University Bochum Department of Medicine I, St Josef-Hospital Gudrunstr. 56 44791 Bochum GermanyP. R. Ritter, Ruhr-University Bochum Department of Medic...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Diabetic ketoacidosis at diagnosis in Austrian children in 1989?2008: a population-based analysisConclusions The overall frequency of DKA in children with newly diagnosed type 1 diabetes in Austria is high and has not changed during
the last 20 years despite a clear increase in the manifestation rate. In particular, children less than 2 years of age have
a high risk of DKA at onset.
Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-010-1704-1Authors
E. Schober, Medical University of Vienna Department of Pediatrics Währinger Gürtel 18?20 1090 Vienna AustriaB. Rami, Medical University of Vienna Department of Pediatrics Währinger Gürtel 18?20 1090 Vienna AustriaT. Waldhoer, Medical University of Vienna Department of Epidemiology, Center of Public Health Vienna Austriaon behalf of the Austrian Diabetes Incidence Study Group
Jou...Impact of metabolic indices on central artery stiffness: independent association of insulin resistance and glucose with aortic pulse wave velocityConclusions/interpretation IGR characterised by fasting or post-challenge hyperglycaemia is associated with significant vascular stiffening. Post-challenge
glucose and HOMA-IR are the most powerful metabolic predictors of arterial stiffness, implying hyperglycaemic excursion and
insulin resistance play important roles in the pathogenesis of arteriosclerosis.
Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-010-1689-9Authors
D. R. Webb, University of Leicester Diabetes and Vascular Research Group, Department of Cardiovascular Sciences Leicester LE1 5WW UKK. Khunti, University of Leicester Department of Health Sciences Leicester UKR. Silverman, University of Leicester Diabetes and Vascular Research Group, Department of Cardiovascular Sciences Leicester L...High normal fasting glucose level in obese youth: a marker for insulin resistance and beta cell dysregulationConclusions/interpretation These data suggest that in obese youth, independent of age, BMI z score, sex, family history and ethnicity, insulin sensitivity and secretion decline when moving from low to high normal fasting
plasma glucose. The simple measure of fasting plasma glucose could assist clinicians in identifying children for targeted
diabetes screening and subsequent lifestyle management.
Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-010-1693-0Authors
G. O?Malley, Yale University School of Medicine Department of Pediatrics 330 Cedar Street PO Box 208064 New Haven CT 06520 USAN. Santoro, Yale University School of Medicine Department of Pediatrics 330 Cedar Street PO Box 208064 New Haven CT 06520 USAV. Northrup, Yale Center for Clinical Inv...Gender-related differences in outcome after ST-segment elevation myocardial infarction treated by primary angioplasty and glycoprotein IIb?IIIa inhibitors: insights from the EGYPT cooperationThis study shows that in patients with STEMI treated by primary angioplasty, female gender is associated with higher
mortality rate in comparison with men, and this is mainly due to their higher clinical and angiographic risk profiles. In
fact, female sex did not emerge as an independent predictor of mortality.
Content Type Journal ArticleDOI 10.1007/s11239-010-0451-yAuthors
Giuseppe De Luca, Eastern Piedmont University Division of Cardiology, Maggiore della Carità Hospital Novara ItalyC. Michael Gibson, Harvard Medical School Beth Israel Deaconess Medical Center Boston USAMariann Gyöngyösi, Medical University of Vienna Department of Cardiology Vienna AustriaUwe Zeymer, Herzzentrum Ludwigshafen Division of Cardiology Ludwigshafen GermanyDariusz Dudek, Jagiellonian University II...The Association Between Gestational Diabetes Mellitus and Recreational Physical ActivityAbstract We aimed to investigate the association of recreational physical activity before pregnancy with gestational diabetes mellitus
(GDM). A cross-sectional study was performed using self-reported data from the Pregnancy Risk Assessment and Monitoring System.
The study population included 1,052 self-reported GDM cases and 10,351 non-GDM controls. Recreational physical activity in
the 3 months before pregnancy was recalled in postpartum structured interviews. Compared to women exercising less than 1 day
per week, women who exercised >5 days per week in the 3 months before pregnancy had a 31% lower odds of GDM (adjusted odds
ratio [aOR]: 0.69; 95% confidence interval [CI]: 0.46, 1.03). Women who exercised 1?4 days per week had a 7% lower odds ...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIPAbstract Steroid therapy appeared to be a standard treatment for autoimmune pancreatitis (AIP), although some AIP patients improve
spontaneously. The indications for steroid therapy in AIP patients are symptoms such as obstructive jaundice, abdominal pain,
and back pain, and the presence of symptomatic extrapancreatic lesions. Before steroid therapy, jaundice should be managed
by biliary drainage in patients with obstructive jaundice, and blood glucose levels should be controlled in patients with
diabetes mellitus. For the initial oral prednisolone dose for induction of remission, 0.6 mg/kg/day is recommended. The initial
dose is administered for 2?4 weeks, and the dose is tapered by 5 mg every 1?2 weeks, based on changes in the clinical manifestatio...Diabetics on hemodialysis in El-Minia Governorate, Upper Egypt: five-year studyConclusion Diabetic nephropathy among HD patients in El-Minia Governorate is increasing but is less prevalent than in the United States
and other Western countries, probably because of a higher incidence of other causes of ESRD in El-Minia governorate, or because
of premature death of diabetic patients. Therefore, meticulous management of diabetic patients is mandatory.
Content Type Journal ArticleCategory Nephrology ? Original PaperDOI 10.1007/s11255-010-9713-zAuthors
Osama El-Minshawy, El Minia University School of Medicine Department of Internal Medicine El Minia EgyptEmad G. Kamel, El Minia University School of Medicine Department of Public Health El Minia Egypt
Journal International Urology and NephrologyOnline ISSN 1573-2584Print ISSN 0301-1623 (Sourc...Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathyAbstract Enhanced production of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) in diabetes leads to degradation
of extracellular matrix in blood vessels and leads to complications of diabetes. In the present study, we have targeted MMP-2
and MMP-9 overactivation in diabetic neuropathy using a known MMP-2 and MMP-9 inhibitor, minocycline, with a non-selective
COX inhibitor, aspirin. Streptozotocin-induced diabetic neuropathy was carried out in male Wistar rats and monitored by measuring
the sensory nerve conduction velocity (SNCV), motor nerve conduction velocity (MNCV), tail flick latency and hot plate latency.
Three weeks of treatment with a combination of minocycline and aspirin showed significant improvement in SNCV, MNCV, hot plate
latency an...Influence of Lys656asn Polymorphism of Leptin Receptor Gene on Surgical Results of Biliopancreatic DiversionConclusion Weight loss was higher in mutant group (Lys656Asn and Asn656Asn) than wild-type group (Lys656Lys) after bariatric surgery.
Carriers of the allelic variant (Asn) had higher basal weight.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s11605-010-1181-3Authors
Daniel Antonio de Luis, University of Valladolid Institute of Endocrinology and Nutrition, Medicine School. Unit of Investigation and Endocrinology Department, Hospital Rio Hortega Valladolid 47130 SpainRocio Aller, University of Valladolid Institute of Endocrinology and Nutrition, Medicine School. Unit of Investigation and Endocrinology Department, Hospital Rio Hortega Valladolid 47130 SpainManuel González Sagrado, University of Valladolid Institute of Endocrinology and Nutrition, Me...Insulin glargine effective for treating nonobese and obese Type 2 diabeticsResults from a subgroup analysis of the ATLANTUS trial show that treatment with insulin glargine is effective for lowering glycated hemoglobin, without substantial weight gain, in obese and nonobese individuals with Type 2 diabetes. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Editorial Board(Source: Diabetes Research and Clinical Practice)Sitagliptin: A Review of its Use in the Management of Type 2 Diabetes Mellitus(Source: Drugs)Circulating osteocalcin concentrations are associated with parameters of liver fat infiltration and increase in parallel to decreased liver enzymes after weight lossConclusions In summary, our findings suggest a bone?liver axis in which osteocalcin might be the active regulator.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1174-9Authors
J. M. Fernández-Real, Institut d?Investigació Biomédica de Girona (IdIBGi) CIBEROBN Fisiopatología de la Obesidad y Nutrición CB06/03/010 Department of Diabetes, Endocrinology and Nutrition Girona Catalonia SpainF. Ortega, Institut d?Investigació Biomédica de Girona (IdIBGi) CIBEROBN Fisiopatología de la Obesidad y Nutrición CB06/03/010 Department of Diabetes, Endocrinology and Nutrition Girona Catalonia SpainJ. Gómez-Ambrosi, University of Navarra Department of Endocrinology Pamplona SpainJ. Salvador, University of Navarra Department of Endocrinology P...The hormonal profile of hip fracture female patients differs from community-dwelling peers over a 1-year follow-up periodConclusions Older women who have sustained a hip fracture have progressive changes in hormonal milieu that exceed those of women of similar
health status during the year following fracture.
Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00198-010-1187-4Authors
A. R. Cappola, University of Pennsylvania School of Medicine Division of Endocrinology, Diabetes and Metabolism 764 CRB, 415 Curie Blvd. Philadelphia PA 19104 USAW. G. Hawkes, University of Maryland Division of Gerontology, Department of Epidemiology and Preventive Medicine Baltimore MD USAN. Blocher, Albert Einstein Medical Center Division of Endocrinology Philadelphia PA USAJ. Yu-Yahiro, The Union Memorial Hospital Department of Orthopaedic Surgery Baltimore MD USAD. Orwig, University of...Effects of antioxidants on postprandial oxidative stress and endothelial dysfunction in subjects with impaired glucose tolerance and Type 2 diabetesConclusions In diabetic subjects, altered glycaemia and lipaemia are closely correlated with markers of systemic oxidative stress. Our
results show that the abnormal changes in oxidative-reductive balance parameters are paralleled by similar changes in markers
of endothelial dysfunction and inflammation at 4 h after ingestion of a fatty meal. Supplementation with a pool of antioxidants
can reduce oxidative stress and inflammation in healthy subjects and, more importantly, in IGT patients. This previous aspect
suggests that the timing of antioxidant supplementation has an important role in endothelium protection in healthy and pre-diabetic
subjects, and along with prompt antioxidant treatment before irreversible endothelial damage has occurred, may have an important
pr...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Hemoglobin A1c outperforms fasting glucose for risk predictionMeasurements of hemoglobin A1c (HbA1c) more accurately identify persons at risk for clinical outcomes than the commonly used measurement of fasting glucose, according to a new study. HbA1c levels accurately predict future diabetes, and they better predict stroke, heart disease and all-cause mortality as well. (Source: ScienceDaily Headlines)Prevalence of dementia disorders in the oldest-old: an autopsy studyAbstract The prevalence of Alzheimer disease (AD) and vascular dementia (VD) increases with advancing age, but less so after age 90 years.
A retrospective hospital-based study of the relative prevalence of different disorders was performed in 1,110 consecutive
autopsy cases of demented elderly in Vienna, Austria (66% females, MMSE <20; mean age 83.3 ± 5.4 SD years). It assessed clinical,
general autopsy data and neuropathology including immunohistochemistry. Neuropathologic diagnosis followed current consensus
criteria. Four age groups (7?10th decade) were evaluated. In the total cohort AD pathology was seen in 82.9% (?pure? AD 42.9%;
AD + other pathologies 39.9%), VD in 10.8% (mixed dementia, MIX, i.e. AD + vascular encepha...Missing published and unpublished data in guidelines(Source: BMJ Online First)Features at Diagnosis of 324 Patients With Acromegaly Did Not Change Fom 1981 to 2006: Acromegaly Remains Under-recognized and Under-diagnosedTraditionally, acromegaly evaded diagnosis until in its clinically obvious later stages when treatment is more difficult. Clinical Endocrinology (Source: Medscape Today Headlines)One's Enough: People Who Donate a Kidney Live Just as Long as Those Who Don'tEvery 30 minutes, all of the blood in our bodies is filtered through two fist-size kidneys. But diseases such as diabetes can cause them to fail, leading to a build-up of chemicals in the blood that without dialysis (mechanical blood filtration) or a kidney transplant would be fatal. And the wait for a new kidney can be long, unless someone you know is willing to give one of theirs to you. [More] (Source: Scientific American Topic - Medical Technology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Endocrinology & Diabetes Research Associate - University of ManchesterAdded via the University of Manchester jobs page.
The Endocrinology and Diabetes group at the University of Manchester have an exciting opening for a postdoctoral Research Associate for up to 5 years, funded by a Wellcome Trust fellowship programme awarded to Professor Neil Hanley.
The successful applicant will study the mechanisms by which pancreatic beta-cells arise during development, with the aim of providing new insights into beta-cell regeneration. Evidence of a productive research background, ideally relating to the pancreas, is required.
The deadline for applications is 18 March 2010. Please visit the University of Manchester jobs page (below) for more information.
Further details (Source: Society for Endocrinology)One's Enough: People Who Donate a Kidney Live Just as Long as Those Who Don'tEvery 30 minutes, all of the blood in our bodies is filtered through two fist-size kidneys. But diseases such as diabetes can cause them to fail, leading to a build-up of chemicals in the blood that without dialysis (mechanical blood filtration) or a kidney transplant would be fatal. And the wait for a new kidney can be long, unless someone you know is willing to give one of theirs to you. [More] (Source: Scientific American - Official RSS Feed)Hepatitis C And Insulin Resistance - Surprising FindingsWe have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance occurs in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease... (Source: Health News from Medical News Today)Hepatitis C And Insulin Resistance - Surprising FindingsWe have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes... (Source: Diabetes News From Medical News Today)Diamyd Medical: Diamyd US Phase III Study Well under WaySTOCKHOLM--(HSMN NewsFeed)--Diamyd Medical (STO:DIAMB)(Pink Sheets:DMYDY ) announces today that one hundred study participants have been included in the ongoing US Phase III study, DiaPrevent. The global Phase III program with the company’s lead drug candi... Biopharmaceuticals, EndocrinologyDiamyd Medical, DiaPrevent, Diamyd, diabetes (Source: HSMN NewsFeed)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Professor Discovers Link Between Low Oxygen Levels In Body And Cancer-Aiding Protein; Could Help Treatments For Retinoblastoma, Breast CancerWhat began as research into how diabetics could possibly preserve their eyesight has led to findings that could prolong the vision of children afflicted with retinoblastoma. Dolores Takemoto, a Kansas State University professor of biochemistry who was researching protein kinase C gamma in the lens of the human eye, found her work taking a fascinating turn when she discovered a correlation between the protein Coonexin46 and hypoxia -- a deficiency of oxygen which kills normal tissue cells. According to the data, Coonexin46, or Cx46, appears in the body during these levels of low oxygen... (Source: Health News from Medical News Today)Starting Treatment Early Doubles Chance Of Success For People With DiabetesThe sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association. The study found that metformin, an inexpensive, generic drug that helps patients prevent dangerously high blood sugar levels, worked nearly twice as long for people who began taking it within three months of their diabetes diagnosis. This is the first study to compare metformin failure rates in a real-world, clinical practice setting... (Source: Health News from Medical News Today)Professor Discovers Link Between Low Oxygen Levels In Body And Cancer-Aiding Protein; Could Help Treatments For Retinoblastoma, Breast CancerWhat began as research into how diabetics could possibly preserve their eyesight has led to findings that could prolong the vision of children afflicted with retinoblastoma... (Source: Breast Cancer News From Medical News Today)Starting Treatment Early Doubles Chance Of Success For People With DiabetesThe sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association... (Source: Diabetes News From Medical News Today)Dr. Gabriel Cousens reveals method for reversing diabetes with raw living foods in exclusive interview(NaturalNews) This is a "must listen" interview for anyone suffering from diabetes, obesity or blood sugar disorders. It's commercial-free and it's a free download of an MP3 file that will play on any computer or MP3 player. What you'll hear in this interview will absolutely astound you -- it rocks the world of conventional medicine and its failed diabetes treatments.This is an interview with Dr. Gabriel Cousens, founder of the Tree of Life Rejuvenation Center in Patagonia, Arizona (www.TreeofLife.nu). In this audio interview, you'll hear Dr. Cousens describe why and how consuming raw foods really works to initiate dramatic reductions in fasting blood sugar levels, effectively reversing diabetes in a matter of just a few weeks.This is essentially a cure for diabetes. Not coincidentally, Dr...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Over 130,000 cases of diabetes now linked to soda consumption, HFCS(NaturalNews) For years, advocates of natural health have been hammering away at the message that soda causes diabetes and obesity. The soda industry, meanwhile, has remained in denial mode, mirroring the ridiculous position of the tobacco industry that "nicotine is not addictive." Soda doesn't cause diabetes, the industry claims, and it's perfectly safe to consume in essentially unlimited quantities.The Corn Refiners Association has joined the denial with its own spin campaign that seeks to convince people High-Fructose Corn Syrup (HFCS) is totally natural and completely harmless. HFCS is, of course, the primary sweetener used in sodas and soft drinks.Now comes new research presented at the American Heart Association's Cardiovascular Disease Epidemiology and Prevention annual conference i...Health Tip: Are You at Greater Risk of Pneumonia?Title: Health Tip: Are You at Greater Risk of Pneumonia?Category: Health NewsCreated: 3/9/2010 10:10:00 AMLast Editorial Review: 3/10/2010 (Source: MedicineNet Diabetes General)Cost of Junk Food May Influence ConsumptionTitle: Cost of Junk Food May Influence ConsumptionCategory: Health NewsCreated: 3/9/2010 10:10:00 AMLast Editorial Review: 3/10/2010 (Source: MedicineNet Diabetes General)Alzheimer's 'Epidemic' Hitting Minorities HardestTitle: Alzheimer's 'Epidemic' Hitting Minorities HardestCategory: Health NewsCreated: 3/9/2010 10:10:00 AMLast Editorial Review: 3/10/2010 (Source: MedicineNet Diabetes General)Obese Colon Cancer Survivors Face Poorer PrognosisTitle: Obese Colon Cancer Survivors Face Poorer PrognosisCategory: Health NewsCreated: 3/9/2010 2:10:00 PMLast Editorial Review: 3/10/2010 (Source: MedicineNet Diabetes General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Most Drug Studies Don't Help Docs Pick Best TreatmentTitle: Most Drug Studies Don't Help Docs Pick Best TreatmentCategory: Health NewsCreated: 3/9/2010 4:10:00 PMLast Editorial Review: 3/10/2010 (Source: MedicineNet Diabetes General)Nitric oxide-releasing wrap for donor organs and cloth for therapeutic socks(American Chemical Society) Scientists in Texas are reporting development of a first-of-its-kind cloth that releases nitric oxide gas -- an advance toward making therapeutic socks for people with diabetes and a wrap to help preserve organs harvested for transplantation. The study is in ACS' Chemistry of Materials, a bi-weekly journal. (Source: EurekAlert! - Medicine and Health)Sodium-Glucose Co-Transport Inhibitors: Progress and Therapeutic Potential in Type 2 Diabetes Mellitus(Source: Drugs)Diabetes drug effective if taken earlyPORTLAND, Ore., March 9 (UPI) -- The sooner people with diabetes take the generic drug Metformin that helps prevent high blood sugar levels, the longer it is effective, U.S. researchers said. (Source: Health News - UPI.com)Scotland backs saxagliptin for type-2 diabetesPeople in Scotland with type-2 diabetes now have access to a wider choice of treatments after saxagliptin (Onglyza) was accepted for use within NHS Scotland. (Source: HealthcareRepublic Press Releases)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Resting Heart Rate and Metabolic Syndrome in Patients With Diabetes and Coronary Artery Disease in Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) TrialPrev Cardiol. ****;**:**[ndash]**. The relation between the metabolic syndrome (MetS) and resting heart rate (rHR) in patients with diabetes and coronary artery disease is unknown. The authors examined the cross-sectional association at baseline between components of the MetS and rHR and between rHR and left ventricular ejection fraction in the population from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized clinical trial. The mean rHR in the MetS group was significantly higher than in those without (68.4±12.3 vs 65.6±11.8 beats per min, P=.0017). The rHR was higher (P (Source: Preventive Cardiology)Drug utilization of oral hypoglycemic agents in a university teaching hospital in IndiaConclusion: This study strongly highlights the need for patient education or counselling on use of antidiabetic and concomitant drugs, monitoring of blood glucose and glycosylated haemoglobin (HbA1c) levels, diet control, and correction of diabetic complications. Metabolic control was poor and HbA1c monitoring was underutilized. Clinical monitoring of patients' adherence to prescribed treatments is recommended and measures should be taken to improve it. (Source: Journal of Clinical Pharmacy and Therapeutics)JinQi-Jiangtang tablet, a Chinese patent medicine, for pre-diabetes: a randomized controlled trialDiscussionThe aim of this study is to evaluate the effectiveness and safety of JinQi JiangTang (JQJT) tablets for the treatment of patients with pre-diabetes.Trial registrationChinese clinical trials register ChiCTR-TRC-00000401 (Source: Trials)Non-Langerhans cell histiocytosis with isolated CNS involvement: An unusual variant of Erdheim-Chester diseaseWe report a 58-year-old Caucasian woman who presented with diabetes insipidus and was found to harbor a large suprasellar mass. Histopathological analysis was consistent with non-LCH. The differential diagnoses included juvenile xanthogranuloma, adult-onset xanthogranuloma, xanthoma disseminatum, Rosai-Dorfman disease, and Erdheim-Chester disease. Immunohistochemical examination demonstrated a proliferation of large lipid-laden histiocytic cells which were positive for CD68, negative for S100 protein, and showed only faint, background staining for CD1a. We present a case of an autopsy-confirmed non-Langerhans cell histiocytosis limited to the central nervous system and evaluated with both immunohistochemical and ultrastructural studies. Based on the multifocality, anatomic distribution, an...A high-protein low-fat diet is more effective in improving blood pressure and triglycerides in calorie-restricted obese individuals with newly diagnosed type 2 diabetesAuthors: E Papakonstantinou, D Triantafillidou, D B Panagiotakos, A Koutsovasilis, M Saliaris, A Manolis, A Melidonis
& A Zampelas (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes MellitusBristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) announced the commencement of the "Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus" trial (SAVOR-TIMI 53), a multicenter, randomized, double-blind, placebo-controlled Phase 4 study, to evaluate treatment with ONGLYZA? (saxagliptin), a dipeptidyl peptidase-4 (DPP4) inhibitor, in adult type 2 diabetes patients with cardiovascular risk factors. (Source: World Pharma News)iViva Bien!: Overcoming Recruitment Challenges in a Multiple-Risk-Factor Diabetes TrialConclusions: Using appropriate recruitment procedures, a representative sample of Latinas can be obtained. (Source: American Journal of Health Behavior)March is "Save Your Vision" MonthDid you know that diabetic retinopathy is a leading cause of blindness in the U.S. today? According to the National Diabetes Information Clearinghouse, between 12,000 to 24,000 new cases of blindness every year are attributed to diabetes.
If you have diabetes, what can you do to protect your vision?
Try to keep your blood sugar levels in a normal range. High blood sugar can damage delicate blood vessels in the eye.
Visit an eye doctor regularly for checkups.
If you notice any changes in your vision, call your eye doctor immediately.
More from your diabetes guide...
What to Know About Diabetic Retinopathy
Photo courtesy of Medioimages/Photodisc/Getty Images
March is "Save Your Vision" Month originally appeared on About.com Diabetes on Wednesday, March 10th, 2010 at 01:03:01.Permalink | ...WBC linked to metabolic syndrome risk, severe psychiatric symptoms in schizophreniaWhite blood cell count may be useful for predicting the metabolic syndrome and more severe psychiatric symptoms in non-diabetic patients with schizophrenia, say US researchers. (Source: MedWire News - Psychiatry)Protect Your Kidneys, Control Diabetes, Op-edNOTE: The following is an op-ed piece by Susan MacNeil, manager, Nova Scotia Renal Program.
Diabetes is the leading cause of kidney disease. More than 40 per cent of people that need dialysis also have diabetes. (Source: Government of Nova Scotia News Releases - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>Beneficial Effects of L- and N-type Calcium Channel Blocker on Glucose and Lipid Metabolism and Renal Function in Patients with Hypertension and Type II Diabetes MellitusThis study was undertaken to compare the efficacy of amlodipine (an inhibitor of L-type calcium channels) and cilnidipine (an inhibitor of both L-type and N-type calcium channels) in patients with hypertension and type II diabetes mellitus. Seventy-seven hypertensive patients were divided into two groups according to presence/absence of type II diabetes mellitus. In these two groups of patients, the effects of amlodipine and cilnidipine on glucose and lipid metabolism and renal function were compared. As for glucose and lipid metabolism, homeostasis model assessment insulin resistance (HOMA-R) level in the non-diabetic group and triglyceride in the diabetes group were significantly lower with cilnidipine than with amlodipine. As regards renal function in the diabetic group, estimated glome...Paradoxical Decrease in High-Density Lipoprotein Cholesterol with Fenofibrate: A Quite Rare Phenomenon IndeedSome recent clinical reports have suggested that paradoxical decreases in high-density lipoprotein cholesterol (HDL-C) levels after fenofibrate treatment may be quite common. These appear to occur mainly in patients with combined fibrate/statin therapy and possibly in those with low baseline HDL-C. Reports on HDL-C reductions after fenofibrate are possibly supported by the disappointing results in terms of HDL-C responses from the recent FIELD study. A survey on 581 patients treated for 1 year or longer was carried out in our Clinical Center. This indicated that paradoxical HDL-C reductions are a relatively uncommon phenomenon. Not more than 15.3% of the present series showed an HDL-C reduction, mostly of a modest degree. Further, reductions of HDL-C appear to occur mainly in individuals w...Targeting the pentose phosphate pathway in syndrome X-related cardiovascular complicationsSyndrome X is a combination or co-occurrence of several known cardiovascular risk factors (including central obesity, dyslipidemias, fatty liver disease, hyperinsulinemia, insulin resistance, and hypertension) that affects at least one in five people in developed countries. Syndrome X shortens life and increases morbidity by contributing to the development of both diabetes and cardiovascular disease. Type 1 or 2 diabetes affects approximately 170 million people globally, and these numbers are rapidly rising. In patients with diabetes, vascular diseases develop early and progress at an accelerated rate. It has recently become evident that glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme in the pentose-phosphate pathway and its reaction products play key roles in regulating...Evaluation of risk of overall mortality in patients with type 2 diabetes receiving glipizide, glyburide, or glimepiride monotherapySource: Diabetes Care
Area: News
According to research published early online in Diabetes Care, glimepiride may be the preferred sulfonylurea in those with underlying coronary artery disease (CAD).
Researchers evaluated the relationship of individual sulfonylureas and the risk of overall mortality in a cohort of patients with type 2 diabetes. The retrospective cohort study was conducted using an academic health centre enterprise-wide electronic health record (EHR) system to identify 11,141 patients with type 2 diabetes (4,279 initiators of monotherapy with glyburide, 4,325 initiators of monotherapy with glipizide, and 2,537 initiators of monotherapy with glimepiride), aged >18 years, with and without a history of CAD, and not on insulin or a non-insulin injectable at baselin...
loss drug also helps in balancing cholesterol. Usage of Acomplia With all the diet supplements Acomplia weight loss drug should be taken on regular basis. Along with regular exercise and diet plan, Acomplia helps to lose weight. To avoid sudden weight gain Acomplia weight loss drug should be taken on a regular basis. Any one suffering from kidney problems, galactose intolerance, psychiatric and liver problems should not take Acomplia weight loss drug before consulting a doctor. Pregnant women and children under 18 should not take Acomplia diet pill. Side effects of Acomplia Acomplia has several side effects which may include mood swings, vomiting, depression and some sleeping disorders. Availability of Acomplia weight loss drug Acomplia weight loss drug can be bought online from the manufacturer's site, by email, via fax or over the telephone. Acomplia weight loss drug can also be bought from any of the online pharmacies. Acomplia weight loss drug is available in 20 gm pills. There are 28 tablets in a pack, 56, 84, 168 and 336 tablets in a pack. As the number of tablets increases in a pack then there is more discount. Acomplia weight loss drug is also believed to restrict CB1 receptors. Acomplia weight loss drug is almost available in every country of Europe and is also available in many countries of Asia, Africa and Australia. For more information about Acomplia please visit: http://www.4rx.com/online-pharmacy/categories/weight-loss/generic-acomplia.html?kbid=7812 Here you will also find an online health specialist who will help you to decide the best weight loss program for you. This health specialist will guide you for your dieting and routine of your regular exercise. If a health specialist chat box does not comes from the left side of the browser, then please refresh the browser and you will get a chat box from the left. David Albert is a Weight Loss expert and author of many weight loss reports. He helped thousands of people losing their weight.
Here are some more diabetes articles...
Obesity Is Not The Fault Of Individuals - Know About Obesity And Its Medicine Acomplia. By Rythm Desai A new report published today supported by the UK government has revealed that individuals should not be held responsible for obesity problems. The news comes just days after the UK health secretary Read more...
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Diabetes Management By Eric Court, Thu Dec 8th Diabetes management is something that many must deal with on aday-to-day basis. About 16 million Americans suffer fromdiabetes mellitus, a chronic disease in which the pancreasproduces too little Read more...
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Smith, Albert F 1,*; Baxter, Suzanne Domel 2; Hardin, James W 3; Guinn, Caroline H 2; Royer, Julie A 2; Litaker, Mark S 4
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Hendricks, M 1,*; Beardsley, J 2; Bourne, L 3; Mzamo, B 1,3; Golden, B 2
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Su, Dada 1; Zhao, Yun 1; Binns, Colin 1,*; Scott, Jane 2; Oddy, Wendy 1
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